Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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NKG2A&CD94 hFc Chimera, Flag, Human
Item number: GSC-Z05683-100
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK...
| Keywords: | KLRC1, NK cell receptor A, NKG2-A/B-activating NK receptor, CD159 antigen-like family member A, NKG2-A/NKG2-B type II... |
| Origin: | human |
| MW: | 17.9/41.1 kD |
From 524.00€
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NKG2C&CD94, His & Avi, Flag Human
Item number: GSC-Z05688-100
NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the...
| Keywords: | KLRC2, NK cell receptor C, NKG2-C-activating NK receptor, CD159 antigen-like family member C, NKG2-C type II integral... |
| Origin: | human |
| MW: | 15.3/17.9 kD |
From 524.00€
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NKG2C/CD159c hFc Chimera, Human
Item number: GSC-Z05689-100
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential...
| Keywords: | KLRC2, NK cell receptor C, NKG2-C-activating NK receptor, CD159 antigen-like family member C, NKG2-C type II integral... |
| Origin: | human |
| MW: | 42.07 kD |
From 524.00€
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NKG2C/CD159c, His & Avi, Human
Item number: GSC-Z05690-100
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential...
| Keywords: | KLRC2, NK cell receptor C, NKG2-C-activating NK receptor, CD159 antigen-like family member C, NKG2-C type II integral... |
| Origin: | human |
| MW: | 15.3 kD |
From 497.00€
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NKp80/CLEC5C hFc Chimera, Human
Item number: GSC-Z05697-100
NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release.
| Keywords: | KLRF1, Activating coreceptor NKp80, C-type lectin domain family 5 member C, Killer cell lectin-like receptor subfamily F... |
| Origin: | human |
| MW: | 45.37 kD |
From 524.00€
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NMNAT1, His, Human
Item number: GSC-Z05698-100
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential...
| Keywords: | NMNAT1, Nicotinate-nucleotide adenylyltransferase 1, Nicotinamide-nucleotide adenylyltransferase 1, Nicotinamide/nicotinic... |
| Origin: | human |
| MW: | 33.46 kD |
From 497.00€
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Noggin, Human
Item number: GSC-Z05699-100
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell...
| Keywords: | NOG, Noggin |
| Origin: | human |
| MW: | 23.05 kD |
From 457.00€
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Notch 1, His & Avi, Human
Item number: GSC-Z05701-100
Human Notch-1 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes.Notch-1 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation...
| Keywords: | NOTCH1, Neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1 |
| Origin: | human |
| MW: | 56.5 kD |
From 457.00€
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NRG1 Beta 1 hFc Chimera, Human
Item number: GSC-Z05710-100
Neuregulin-1 (NRG-1) is a ligand of the epidermal growth factor receptor (erbB), and its interaction involves activation of the glutamatergic N-methyl-Daspartate receptor, which increases the expression of the beta2 subunit of the gamma- aminobutyric acid receptor and subunits of the nicotinic acetylcholine receptor.
| Keywords: | NRG1, Pro-neuregulin-1, membrane-bound isoform |
| Origin: | human |
| MW: | 54 kD |
From 363.00€
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NUDT5, His, Human
Item number: GSC-Z05712-100
NUDIX hydrolase type 5 (NUDT5) is a kind of ADP-ribose pyrophosphatase and nucleotide metabolizing enzyme in cell metabolism. NUDT5 expression affected chromosome remodeling, involved in cell adhesion, cancer stem cell maintenance and epithelial to mesenchyme transition in breast cancer cells.
| Keywords: | YSA1H, NUDT5, 8-oxo-dGDP phosphatase, ADP-sugar pyrophosphatase, Nuclear ATP-synthesis protein NUDIX5, Nucleoside... |
| Origin: | human |
| MW: | 25.29 kD |
From 497.00€
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OSMR beta-GPL fusion, His, Human
Item number: GSC-Z05722-100
OSMR involvement, together with Gp130-like receptor (GPL), also known as IL-31R, in the formation of a functional IL-31 receptor complex. OSMR-GPL fusion protein was designed to contain the domains of OSMR and GPL required for high affinity IL-31 binding.
| Keywords: | GLM-R, IL31RA, ZcytoR17, Cytokine receptor-like 3, Gp130-like monocyte receptor, Interleukin-31 receptor subunit alpha |
| Origin: | human |
| MW: | 75.84 kD |
From 632.00€
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PD-L1/B7-H1, His, Human
Item number: GSC-Z05744-100
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune...
| Keywords: | CD274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Origin: | human |
| MW: | 26 kD |
From 457.00€
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