Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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IL-17RB, His, Human
Item number: GSC-Z05448-100
Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway...
| Keywords: | IL17RB, Cytokine receptor-like 4, Interleukin-17B receptor, IL-17 receptor homolog 1, Interleukin-17 receptor B |
| Origin: | human |
| MW: | 31.4 kD |
From 497.00€
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IL-18RAP/IL-18 R beta hFc Chimera, Human
Item number: GSC-Z05455-100
lactoferrin (LTF), peptidoglycan recognition protein 1 and IL-18 receptor accessory protein (IL18RAP) remained significantly elevated in peripheral monocytes of hypertensive individuals in a separate validation cohort. Interestingly, IL18RAP expression associated with MAP in a cohort of African Americans.
| Keywords: | IL18RAP, CDw218b, Accessory protein-like, Interleukin-1 receptor 7, IL-1R accessory protein-like, Interleukin-18 receptor... |
| Origin: | human |
| MW: | 65.3 kD |
From 457.00€
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IL-21R, His, Human
Item number: GSC-Z05476-100
IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORgammat expression and downregulating Foxp3 expression, with increased expression...
| Keywords: | IL21R, Interleukin-21 receptor, Novel interleukin receptor |
| Origin: | human |
| MW: | 25.65 kD |
From 228.00€
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IL-23R hFc Chimera, Human
Item number: GSC-Z05484-100
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the...
| Keywords: | IL23R, Interleukin-23 receptor |
| Origin: | human |
| MW: | 64.81 kD |
From 524.00€
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IL-23R, His, Human
Item number: GSC-Z05485-100
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the...
| Keywords: | IL23R, Interleukin-23 receptor |
| Origin: | human |
| MW: | 39.15 kD |
From 524.00€
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IL-3, Human
Item number: GSC-Z05490-100
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells,...
| Keywords: | IL3, Interleukin-3, Mast cell growth factor, P-cell-stimulating factor, Hematopoietic growth factor, Multipotential... |
| Origin: | human |
| MW: | 15.09 kD |
From 376.00€
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IL-4 R alpha/CD124, His, Human
Item number: GSC-Z05505-100
Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
| Keywords: | IL4R, Interleukin-4 receptor subunit alpha |
| Origin: | human |
| MW: | 24.7 kD |
From 457.00€
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IL-9, His, Human
Item number: GSC-Z05517-100
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as...
| Keywords: | IL9, Cytokine P40, Interleukin-9, T-cell growth factor P40 |
| Origin: | human |
| MW: | 15.3 kD |
From 524.00€
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IL-9 hFc Chimera, Human
Item number: GSC-Z05518-100
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as...
| Keywords: | IL9, Cytokine P40, Interleukin-9, T-cell growth factor P40 |
| Origin: | human |
| MW: | 40.9 kD |
From 457.00€
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ILDR2 hFc Chimera, Human
Item number: GSC-Z05519-100
Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic...
| Keywords: | ILDR2, Angulin-3, Immunoglobulin-like domain-containing receptor 2 |
| Origin: | human |
| MW: | 35 kD |
From 632.00€
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KIR2DL2, His & Avi, Human
Item number: GSC-Z05545-100
KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is...
| Keywords: | KIR2DL2, CD158 antigen-like family member B1, Natural killer-associated transcript 6, p58 natural killer cell receptor... |
| Origin: | human |
| MW: | 27.4 kD |
From 349.00€
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L1CAM, His, Human
Item number: GSC-Z05555-100
L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and...
| Keywords: | L1CAM, Neural cell adhesion molecule L1 |
| Origin: | human |
| MW: | 124.6 kD |
From 457.00€
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