Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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GDNF, Human
Item number: GSC-Z05344-100
Glial cell line-derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote dopamine uptake within midbrain dopaminergic neurons.
| Keywords: | GDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor |
| Origin: | human |
| MW: | 15.06 kD |
From 578.00€
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GEP, His, Human
Item number: GSC-Z05345-100
Haploinsufficiency of progranulin (PGRN) is a leading cause of frontotemporal lobar degeneration (FTLD). Loss of PGRN leads to lysosome dysfunction during aging. TMEM106B, a gene encoding a lysosomal membrane protein, is the main risk factor for FTLD with PGRN haploinsufficiency.Loss of both PGRN and TMEM106B...
| Keywords: | GRN, Acrogranin, Progranulin, Proepithelin, Granulin precursor, Epithelin precursor, Glycoprotein of 88 Kda, PC... |
| Origin: | human |
| MW: | 62.9 kD |
From 457.00€
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GIP hFc Chimera, Human
Item number: GSC-Z05353-100
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2...
| Keywords: | GIP, Incretin hormone, Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide |
| Origin: | human |
| MW: | 34.9 kD |
From 457.00€
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GIPR hFc Chimera, Human
Item number: GSC-Z05354-100
The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity.
| Keywords: | GIPR, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor |
| Origin: | human |
| MW: | 38.91 kD |
From 457.00€
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GM-CSF, Human
Item number: GSC-Z05361-100
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally...
| Keywords: | CSF2, Sargramostim, Molgramostin, Colony-stimulating factor, Granulocyte-macrophage colony-stimulating factor |
| Origin: | human |
| MW: | 14.6 kD |
From 376.00€
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GPA34/VSIG1, His, Human
Item number: GSC-Z05368-100
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three alternatively spliced isoforms of mouse Vsig1 during pre- and postnatal development of stomach and...
| Keywords: | VSIG1, Glycoprotein A34, Cell surface A33 antigen, V-set and immunoglobulin domain-containing protein 1 |
| Origin: | human |
| MW: | 24 kD |
From 457.00€
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GPVI, His, Human
Item number: GSC-Z05369-100
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor...
| Keywords: | GP6, Glycoprotein 6, Platelet glycoprotein VI |
| Origin: | human |
| MW: | 28 kD |
From 457.00€
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Her4/ErbB4, His & Avi, Human
Item number: GSC-Z05372-100
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue...
| Keywords: | ERBB4, p180erbB4, Proto-oncogene-like protein c-ErbB-4, Receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell... |
| Origin: | human |
| MW: | 72.7 kD |
From 376.00€
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HMGB1, His, Human
Item number: GSC-Z05380-100
High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport...
| Keywords: | HMGB1, High mobility group protein 1, High mobility group protein B1 |
| Origin: | human |
| MW: | 26 kD |
From 524.00€
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HRG/HPRG, His, Human
Item number: GSC-Z05383-100
Histidine-rich glycoprotein (HRG) is a 75 kDa glycoprotein synthesized in the liver whose plasma concentration is 100-150 µg/ml. HRG has been shown to modulate sepsis-related biological reactions by binding to several substances and cells, including heparin, factor XII, fibrinogen, thrombospondin, plasminogen, C1q,...
| Keywords: | HRG, Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein |
| Origin: | human |
| MW: | 58.75 kD |
From 497.00€
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Hsp27/HSPB1, His, Human
Item number: GSC-Z05384-100
Heat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against oxidative stress. This protein is expressed only in insulin-dependent tissues (heart, skeletal muscle, and fat tissue), and expression of HspB7 is regulated...
| Keywords: | HSPB1, 28 kDa heat shock protein, Heat shock protein beta-1, Heat shock 27 kDa protein, Stress-responsive protein 27,... |
| Origin: | human |
| MW: | 23.74 kD |
From 497.00€
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ICOS/CD278 (C136S, C137S), His, Human
Item number: GSC-Z05392-100
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human ICOS is a homodimeric type I transmembrane...
| Keywords: | ICOS, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule |
| Origin: | human |
| MW: | 14.8 kD |
From 551.00€
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