Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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IL-1 Rrp2/IL-1 R6, His, Cynomolgus
Item number: GSC-Z04820-100
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL-1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL-1 (TIGIRR-2/IL-1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a...
| Keywords: | IL1RL2, IL-36 receptor, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2 |
| Origin: | cynomolgus |
| MW: | 37.1 kD |
From 457.00€
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IL-10 R alpha, His, Cynomolgus
Item number: GSC-Z04822-100
The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many inflammatory disorders in livestock, including Johne's disease (JD). JD is a chronic...
| Keywords: | IL10RA, CDw210a, Interleukin-10 receptor subunit 1, Interleukin-10 receptor subunit alpha |
| Origin: | cynomolgus |
| MW: | 25.34 kD |
From 524.00€
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IL-12B/p40/NKSF2, His, Cynomolgus
Item number: GSC-Z04825-100
Interleukin (IL)-12B, which encodes the p40 subunit common to IL-12 and IL-23, as one of the genes for which expression in fibroblast-like synoviocytes from patients with rheumatoid arthritis (RA-FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin-related...
| Keywords: | IL12B, IL-12 subunit p40, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40 kDa subunit |
| Origin: | cynomolgus |
| MW: | 35.86 kD |
From 632.00€
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IL-21R, His, Cynomolgus
Item number: GSC-Z04834-100
IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORgammat expression and downregulating Foxp3 expression, with increased expression...
| Keywords: | IL21R, Interleukin-21 receptor, Novel interleukin receptor |
| Origin: | cynomolgus |
| MW: | 25.7 kD |
From 524.00€
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IL-22R alpha 1, His, Cynomolgus
Item number: GSC-Z04836-100
IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22...
| Keywords: | IL22RA1, Interleukin-22 receptor subunit alpha-1 |
| Origin: | cynomolgus |
| MW: | 24.84 kD |
From 524.00€
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IL-6, His, Cynomolgus
Item number: GSC-Z04846-100
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.
| Keywords: | IL6, Interleukin-6 |
| Origin: | cynomolgus |
| MW: | 22.06 kD |
From 524.00€
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LILRA6/CD85b/ILT8, His, Cynomolgus
Item number: GSC-Z04856-100
The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. Specific allelic variants of two related members of the LILR family, LILRB3 and LILRA6, interact with a ligand exposed on necrotic glandular epithelial cells. The extracellular domains of LILRB3 and LILRA6 are very similar and...
| Keywords: | Ig-like domain-containing protein |
| Origin: | cynomolgus |
| MW: | 48.28 kD |
From 497.00€
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MERTK/Mer, His, Cynomolgus
Item number: GSC-Z04871-100
MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the...
| Keywords: | MERTK, Proto-oncogene c-Mer, Tyrosine-protein kinase Mer, Receptor tyrosine kinase MerTK |
| Origin: | cynomolgus |
| MW: | 53.85 kD |
From 524.00€
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MFAP4, His, Cynomolgus
Item number: GSC-Z04872-100
Microfibril-associated glycoprotein 4 (MFAP4) is an extracellular matrix protein belonging to the fibrinogen-related protein superfamily. MFAP4 is produced by vascular smooth muscle cells and is highly enriched in the blood vessels of the heart and lung, where it is thought to contribute to the structure and...
| Keywords: | MFAP4, Microfibril-associated glycoprotein 4 |
| Origin: | cynomolgus |
| MW: | 27.6 kD |
From 524.00€
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MMP-9, His, Cynomolgus
Item number: GSC-Z04875-100
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To...
| Keywords: | MMP9, Gelatinase B, 92 kDa gelatinase, Matrix metalloproteinase-9, 92 kDa type IV collagenase |
| Origin: | cynomolgus |
| MW: | 77.44 kD |
From 524.00€
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NKG2C/CD159c, His, Cynomolgus
Item number: GSC-Z04881-100
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential...
| Keywords: | nkg2C |
| Origin: | cynomolgus |
| MW: | 16.9 kD |
From 578.00€
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NKp46/NCR1/CD335 hFc Chimera, Cynomolgus
Item number: GSC-Z04882-100
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic...
| Keywords: | NCR1, Natural killer cell p46-related protein, Natural cytotoxicity triggering receptor 1 |
| Origin: | cynomolgus |
| MW: | 53.1 kD |
From 524.00€
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