Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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E-selectin/CD62E, His, Cynomolgus
Item number: GSC-Z04786-100
E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in...
| Keywords: | SELE, L-selectin, Lymph node homing receptor, Leukocyte adhesion molecule 1, CD62 antigen-like family member L,... |
| Origin: | cynomolgus |
| MW: | 59.47 kD |
From 524.00€
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Fc gamma RIIB, His, Cynomolgus
Item number: GSC-Z04787-100
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains, these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on...
| Keywords: | Fc-gamma RIII-alpha, Low affinity immunoglobulin gamma Fc region receptor III-A |
| Origin: | cynomolgus |
| MW: | 21 kD |
From 457.00€
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Fc gamma RIII/CD16, His, Cynomolgus
Item number: GSC-Z04788-100
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set...
| Keywords: | FCGR3A, Fc-gamma RIII-alpha, Low affinity immunoglobulin gamma Fc region receptor III-A |
| Origin: | cynomolgus |
| MW: | 23.1 kD |
From 403.00€
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FGF21, His, Cynomolgus
Item number: GSC-Z04790-100
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss and improved glycemia.
| Keywords: | FGF21, Fibroblast growth factor |
| Origin: | cynomolgus |
| MW: | 20.5 kD |
From 457.00€
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GARP&Latent TGF beta 1 Complex, His & Avi, Cynomolgus
Item number: GSC-Z04797-100
GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-beta and thus promoting secretion and activation of TGF-beta. Integrin alphavbeta8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the...
| Keywords: | LRRC32, Leucine-rich repeat-containing protein 32, Transforming growth factor beta activator LRRC32 |
| Origin: | cynomolgus |
| MW: | 70.5/41.3 kD |
From 524.00€
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HGF R/c-MET, His, Cynomolgus
Item number: GSC-Z04807-100
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which...
| Keywords: | MET, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, Tyrosine-protein kinase Met, Hepatocyte growth factor... |
| Origin: | cynomolgus |
| MW: | 32.5/69.9 kD |
From 524.00€
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HGFA (pro form), His, Cynomolgus
Item number: GSC-Z04808-100
Hepatocyte growth factor activator (HGFA) is a serine protease initially identified as a potent activator of hepatocyte growth factor/scatter factor. Hepatocyte growth factor/scatter factor is known to be critically involved in tissue morphogenesis, regeneration, and tumor progression, via its receptor, MET.In vivo,...
| Keywords: | HGFAC, Hepatocyte growth factor activator |
| Origin: | cynomolgus |
| MW: | 67.47 kD |
From 524.00€
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HPX, His, Cynomolgus
Item number: GSC-Z04809-100
Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker...
| Keywords: | Hemopexin |
| Origin: | cynomolgus |
| MW: | 50.3 kD |
From 524.00€
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IFN gamma/IFNG, His, Cynomolgus
Item number: GSC-Z04813-100
IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with...
| Keywords: | IFNG, Interferon gamma |
| Origin: | cynomolgus |
| MW: | 17.72 kD |
From 524.00€
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IL-1 alpha/IL-1A, Cynomolgus
Item number: GSC-Z04817-100
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1alpha and IL-1beta were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made...
| Keywords: | IL1A, Hematopoietin-1, Interleukin-1 alpha |
| Origin: | cynomolgus |
| MW: | 18.13 kD |
From 578.00€
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IL-1 alpha/IL-1A, His, Cynomolgus
Item number: GSC-Z04818-100
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1alpha and IL-1beta were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made...
| Keywords: | IL1A, Hematopoietin-1, Interleukin-1 alpha |
| Origin: | cynomolgus |
| MW: | 19.23 kD |
From 524.00€
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IL-1 Beta/IL-1F2, His, Cynomolgus
Item number: GSC-Z04819-100
Interleukin-1 beta (IL-1beta) is induced by inflammatory signals in a broad number of immune cell types. IL-1beta (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives...
| Keywords: | IL1B, Multifunctional fusion protein |
| Origin: | cynomolgus |
| MW: | 18.33 kD |
From 524.00€
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