Products from GenScript

GenScript

GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.

More information at: www.genscript.com

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TRAIL R2/DR5/TNFRSF10B[Biotin], His & Avi, Human
TRAIL R2/DR5/TNFRSF10B[Biotin], His & Avi, Human

Item number: GSC-Z04633-100

DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates...
Keywords: TNFRSF10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily...
Origin: human
MW: 17.2 kD
From 887.00€ *
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ULBP-1[Biotin], His & Avi, Human
ULBP-1[Biotin], His & Avi, Human

Item number: GSC-Z04639-100

Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natural killer (NK) cells.
Keywords: ULBP1, ALCAN-beta, NKG2D ligand 1, UL16-binding protein 1, Retinoic acid early transcript 1I
Origin: human
MW: 25.2 kD
From 887.00€ *
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uPAR/PLAUR[Biotin], His & Avi, Human
uPAR/PLAUR[Biotin], His & Avi, Human

Item number: GSC-Z04641-100

The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
Keywords: PLAUR, Monocyte activation antigen Mo3, Urokinase plasminogen activator surface receptor
Origin: human
MW: 34.36 kD
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VEGF121[Biotin], His & Avi, Human
VEGF121[Biotin], His & Avi, Human

Item number: GSC-Z04642-100

Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189.
Keywords: VEGFA, Vascular permeability factor, Vascular endothelial growth factor A, long form
Origin: human
MW: 17 kD
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VEGF-C/Flt4-L[Biotin], His & Avi, Human
VEGF-C/Flt4-L[Biotin], His & Avi, Human

Item number: GSC-Z04644-100

the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not...
Keywords: VEGFC, Flt4 ligand, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein
Origin: human
MW: 17.1 kD
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Cpn10/HSPE1[Biotin], His & Avi, Human/Mouse/Goat
Cpn10/HSPE1[Biotin], His & Avi, Human/Mouse/Goat

Item number: GSC-Z04646-100

Cpn10/HSPE, a 10-kDa heat shock protein, is a novel interacting partner of NPAT. A pool of Cpn10 is colocalized with NPAT foci during G1 and S phases in nuclei.Cpn10 is important for S phase progression and cell proliferation. Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein...
Keywords: HSPE1, Chaperonin 10, 10 kDa chaperonin, 10 kDa heat shock protein, mitochondrial
Origin: human, mouse, goat
MW: 13.7 kD
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CDCP1[Biotin], His & Avi, Mouse
CDCP1[Biotin], His & Avi, Mouse

Item number: GSC-Z04652-100

Tumor metastasis depends on the dynamic regulation of cell adhesion through beta1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
Keywords: Cdcp1, Membrane glycoprotein gp140, CUB domain-containing protein 1, Transmembrane and associated with src kinases
Origin: mouse
MW: 75.3 kD
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Fc gamma RIII/CD16[Biotin], His & Avi, Mouse
Fc gamma RIII/CD16[Biotin], His & Avi, Mouse

Item number: GSC-Z04655-100

Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set...
Keywords: Fcgr3, Fc-gamma RIII, Low affinity immunoglobulin gamma Fc region receptor III
Origin: mouse
MW: 23.97 kD
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GFRAL/GFR alpha-like[Biotin], His & Avi, Mouse
GFRAL/GFR alpha-like[Biotin], His & Avi, Mouse

Item number: GSC-Z04661-100

GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted...
Keywords: Gfral, GDNF family receptor alpha-like
Origin: mouse
MW: 40.1 kD
From 1,008.00€ *
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H-2K(b)&B2M&OVA (SIINFEKL) Monomer[Biotin], His & Avi, Mouse
H-2K(b)&B2M&OVA (SIINFEKL) Monomer[Biotin], His & Avi, Mouse

Item number: GSC-Z04662-100

Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is...
Keywords: B2m, Beta-2-microglobulin
Origin: mouse
MW: 50.2 kD
From 685.00€ *
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IFN alpha/beta R2[Biotin], His & Avi, Mouse
IFN alpha/beta R2[Biotin], His & Avi, Mouse

Item number: GSC-Z04664-100

Although interferon (IFN)-alpha is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-alpha-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is...
Keywords: Ifnar2, Type I interferon receptor 2, Interferon alpha/beta receptor 2
Origin: mouse
MW: 28.34 kD
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IL-23A[Biotin], His & Avi, Mouse
IL-23A[Biotin], His & Avi, Mouse

Item number: GSC-Z04671-100

The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an...
Keywords: Il23a, Interleukin-23 subunit p19, Interleukin-23 subunit alpha
Origin: mouse
MW: 23.41 kD
From 887.00€ *
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44 from 323 pages