Products from GenScript

GenScript

GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.

More information at: www.genscript.com

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CD28[Biotin], His & Avi, Human/Cynomolgus/Rhesus macaque
CD28[Biotin], His & Avi, Human/Cynomolgus/Rhesus macaque

Item number: GSC-Z04102-100

CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Keywords: TP44, CD28, T-cell-specific surface glycoprotein CD28
Origin: human, cynomolgus, rhesus macaque
MW: 18.2 kD
From 887.00€ *
Review
CD200 R1/CRTR2, His, Cynomolgus
CD200 R1/CRTR2, His, Cynomolgus

Item number: GSC-Z04108-100

CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that...
Keywords: CD200R1
Origin: cynomolgus
MW: 28.09 kD
From 524.00€ *
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CD200/OX-2, His, Cynomolgus
CD200/OX-2, His, Cynomolgus

Item number: GSC-Z04109-100

CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models.
Keywords: CD200, OX-2 membrane glycoprotein
Origin: cynomolgus
MW: 23.66 kD
From 524.00€ *
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CD24 hFc Chimera, Cynomolgus
CD24 hFc Chimera, Cynomolgus

Item number: GSC-Z04110-100

CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers.
Keywords: Signal transducer CD24
Origin: cynomolgus
MW: 30.2 kD
From 524.00€ *
Review
CD31/PECAM-1, His, Cynomolgus
CD31/PECAM-1, His, Cynomolgus

Item number: GSC-Z04117-100

Platelet endothelial cell adhesion molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays important roles in angiogenesis, vascular permeability, and regulation of cellular responsiveness.
Keywords: PECAM1, Platelet endothelial cell adhesion molecule
Origin: cynomolgus
MW: 65.3 kD
From 524.00€ *
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CD40/TNFRSF5, His, Cynomolgus
CD40/TNFRSF5, His, Cynomolgus

Item number: GSC-Z04120-100

CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of...
Keywords: CD40, CD40L receptor, B-cell surface antigen CD40, Tumor necrosis factor receptor superfamily member 5
Origin: cynomolgus
MW: 20.3 kD
From 457.00€ *
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CD83, His, Cynomolgus
CD83, His, Cynomolgus

Item number: GSC-Z04127-100

CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic cells (DC). While CD83 is emerging as a promising immune...
Keywords: CD83, CD83 antigen
Origin: cynomolgus
MW: 15.43 kD
From 524.00€ *
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GPC3/Glypican 3, His, Cynomolgus
GPC3/Glypican 3, His, Cynomolgus

Item number: GSC-Z04133-100

Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several...
Keywords: GPC3, Glypican-3
Origin: cynomolgus
MW: 61.8 kD
From 524.00€ *
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NKG2D/CD314, His, Cynomolgus
NKG2D/CD314, His, Cynomolgus

Item number: GSC-Z04137-100

NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma delta T cells, NK cells and NKT...
Keywords: KLRK1, NK cell receptor D, NKG2-D-activating NK receptor, NKG2-D type II integral membrane protein, Killer cell...
Origin: cynomolgus
MW: 17.48 kD
From 524.00€ *
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DPPIV/CD26, His, Cynomolgus/Rhesus macaque
DPPIV/CD26, His, Cynomolgus/Rhesus macaque

Item number: GSC-Z04144-100

CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express DPPIV/CD26 to a variable extent.
Keywords: DPP4, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26
Origin: cynomolgus, rhesus macaque
MW: 86.11 kD
From 524.00€ *
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CD164 hFc Chimera, Human
CD164 hFc Chimera, Human

Item number: GSC-Z04164-100

CD164 was found to play a role in many malignant diseases. CD164 was associated with clinical and pathological features of patients. High level of CD164 was related to the distant metastasis and vascular invasion of bladder cancer patients.CD164 was associated with the poor clinical outcomes of BC patients....
Keywords: CD164, Endolyn, Sialomucin core protein 24, Multi-glycosylated core protein 24
Origin: human
MW: 41.2 kD
From 403.00€ *
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CD200 R1/CRTR2, His & Avi, Human
CD200 R1/CRTR2, His & Avi, Human

Item number: GSC-Z04168-100

CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that...
Keywords: CD200R1, Cell surface glycoprotein OX2 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein...
Origin: human
MW: 29.7 kD
From 457.00€ *
Review
35 from 323 pages