Products from GenScript

GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.

More information at: www.genscript.com

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HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer[Biotin], His...

Item number: GSC-Z06507-100

Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.

Keywords:	B2M, Beta-2-microglobulin
Origin:	human
MW:	50.2 kD

From 685.00€ *

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HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer[Biotin],...

Item number: GSC-Z06508-100

Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.

Keywords:	B2M, Beta-2-microglobulin
Origin:	human
MW:	50.2 kD

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HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer[Biotin],...

Item number: GSC-Z06509-100

Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and...

Keywords:	B2M, Beta-2-microglobulin
Origin:	human
MW:	50.3 kD

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HLA-G&B2M&Peptide (RIIPRHLQL) Monomer[Biotin], His & Avi,...

Item number: GSC-Z06522-100

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or...

Keywords:	B2M, Beta-2-microglobulin
Origin:	rhesus macaque
MW:	50.5 kD

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Chimeric HLA-A*02:01 (m?3) &B2M&LMP2 (CLGGLLTMV) Monomer,...

Item number: GSC-Z06523-100

The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer...

Keywords:	H2-L, H-2 class I histocompatibility antigen, L-D alpha chain
MW:	50.3 kD

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Chimeric HLA-A*02:01 (m?3) &B2M&LMP2 (CLGGLLTMV)...

Item number: GSC-Z06524-100

Keywords:	H2-L, H-2 class I histocompatibility antigen, L-D alpha chain
MW:	258 kD

From 1,505.00€ *

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Chimeric HLA-A*02:01 (m?3) &B2M&WT-1 (RMFPNAPYL)...

Item number: GSC-Z06526-100

The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and...

Keywords:	H2-L, H-2 class I histocompatibility antigen, L-D alpha chain
MW:	258 kD

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HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer, His & Avi,...

Item number: GSC-Z06585-100

p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates...

Keywords:	B2M, Beta-2-microglobulin
Origin:	human
MW:	50.5 kD

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HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer, His & Avi,...

Item number: GSC-Z06595-100

Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers, consequently, it has received significant attention as a...

Keywords:	B2M, Beta-2-microglobulin
Origin:	human
MW:	258 kD

From 1,505.00€ *

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HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer, His & Avi, Human

Item number: GSC-Z06600-100

Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting...