Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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tPA hFc Chimera, Mouse
Item number: GSC-Z06387-100
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism.
| Keywords: | Plat, Tissue-type plasminogen activator |
| Origin: | mouse |
| MW: | 85 kD |
From 497.00€
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tPA, His, Mouse
Item number: GSC-Z06388-100
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism.
| Keywords: | Plat, Tissue-type plasminogen activator |
| Origin: | mouse |
| MW: | 60.57 kD |
From 497.00€
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TPBG/5T4, His, Mouse
Item number: GSC-Z06389-100
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs.
| Keywords: | Tpbg, Trophoblast glycoprotein, Wnt-activated inhibitory factor 1, 5T4 oncofetal trophoblast glycoprotein |
| Origin: | mouse |
| MW: | 36.86 kD |
From 524.00€
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TRAIL R2/DR5/TNFRSF10B, His, Mouse
Item number: GSC-Z06390-100
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling...
| Keywords: | MK, Tnfrsf10b, Death receptor 5, Tumor necrosis factor receptor superfamily member 10B |
| Origin: | mouse |
| MW: | 15.3 kD |
From 336.00€
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TYRO3, His, Mouse
Item number: GSC-Z06396-100
The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew macrophage polarization towards a pro-tumor M2-like phenotype.In macrophages, the TAM receptors also...
| Keywords: | Tyro3, TK19-2, Etk2/tyro3, Tyrosine-protein kinase RSE, Tyrosine-protein kinase TIF, Tyrosine-protein kinase DTK,... |
| Origin: | mouse |
| MW: | 43 kD |
From 457.00€
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uPAR/PLAUR Domain 3, His & Avi, Mouse
Item number: GSC-Z06398-100
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
| Keywords: | Plaur, Urokinase plasminogen activator surface receptor |
| Origin: | mouse |
| MW: | 11.83 kD |
From 524.00€
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uPAR/PLAUR, His & Avi, Mouse
Item number: GSC-Z06399-100
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
| Keywords: | Plaur, Urokinase plasminogen activator surface receptor |
| Origin: | mouse |
| MW: | 32.92 kD |
From 376.00€
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VCAM-1/CD106, His, Mouse
Item number: GSC-Z06400-100
Tumor necrosis factor alpha (TNFalpha) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFalpha induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was...
| Keywords: | Vcam1, Vascular cell adhesion protein 1 |
| Origin: | mouse |
| MW: | 75.48 kD |
From 524.00€
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VNN1, His, Mouse
Item number: GSC-Z06402-100
Vanin-1 (VNN1) is anchored to the cellular membrane with pantetheinase activity, which hydrolyzes pantetheine to produce cysteamine. VNN1 can promote oxidative stress and the inflammatory response. Additionally, VNN1 has been confirmed to be overexpressed in cancer tissues of patients with PCAD and can be used as a...
| Keywords: | Vnn1, Pantetheinase, Pantetheine hydrolase, Vascular non-inflammatory molecule 1 |
| Origin: | mouse |
| MW: | 53.14 kD |
From 457.00€
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VSTM5 hFc Chimera, Mouse
Item number: GSC-Z06403-100
V-set and transmembrane domain-containing protein 5 (Vstm5), a cell-adhesion-like molecule belonging to the Ig superfamily, was found in mouse brain. Knock-down of Vstm5 in cultured hippocampal neurons markedly reduced the complexity of dendritic structures, as well as the number of dendritic filopodia. Vstm5 also...
| Keywords: | Vstm5, V-set and transmembrane domain-containing protein 5 |
| Origin: | mouse |
| MW: | 40.1 kD |
From 457.00€
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WISP1, His, Mouse
Item number: GSC-Z06404-100
The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and secreted by GSCs. Silencing WISP1 markedly disrupts GSC maintenance, reduces tumor-supportive TAMs...
| Keywords: | Ccn4, ELM-1, CCN family member 4, WNT1-inducible-signaling pathway protein 1 |
| Origin: | mouse |
| MW: | 39.4 kD |
From 497.00€
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XPNPEP2, His, Mouse
Item number: GSC-Z06405-100
Aminopeptidase P2 (XPNPEP2) is a receptor for TMTP1 tumor-homing peptide. However, the biological and clinical significance of Aminopeptidase P2 in human cancers remains unknown.
| Keywords: | Xpnpep2, Xaa-Pro aminopeptidase 2, X-prolyl aminopeptidase 2, Membrane-bound aminopeptidase P |
| Origin: | mouse |
| MW: | 72.24 kD |
From 578.00€
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