Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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PGLYRP1 hFc Chimera, Mouse
Item number: GSC-Z06309-100
Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFalpha receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either...
| Keywords: | Pglyrp1, Cytokine tag7, Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short |
| Origin: | mouse |
| MW: | 45.7 kD |
From 497.00€
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PKM2, His, Mouse
Item number: GSC-Z06313-100
Pyruvate kinase M2 (PKM2), a key rate-limiting enzyme of glycolysis, is a critical regulator in tumor metabolism. PKM2 has been demonstrated to overexpressed in various cancers and promoted proliferation and metastasis of tumor cells.
| Keywords: | Pkm, Pyruvate kinase PKM, Tyrosine-protein kinase PKM2, Threonine-protein kinase PKM2, Pyruvate kinase muscle isozyme |
| Origin: | mouse |
| MW: | 58.95 kD |
From 497.00€
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PLA2G1B hFc Chimera, Mouse
Item number: GSC-Z06314-100
Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal transduction. PLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic...
| Keywords: | Pla2g1b, PLA2-Ib, Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B |
| Origin: | mouse |
| MW: | 40.9 kD |
From 457.00€
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PLA2G7, His, Mouse
Item number: GSC-Z06315-100
Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the...
| Keywords: | Pla2g7, PAF 2-acylhydrolase, LDL-associated phospholipase A2, Platelet-activating factor acetylhydrolase,... |
| Origin: | mouse |
| MW: | 47.9 kD |
From 497.00€
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PSMP hFc Chimera, Mouse
Item number: GSC-Z06329-100
PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern...
| Keywords: | Msmp, PC3-secreted microprotein homolog, Prostate-associated microseminoprotein |
| Origin: | mouse |
| MW: | 37.9 kD |
From 457.00€
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SEMA3A, His, Mouse
Item number: GSC-Z06341-100
The CRMP proteins were originally identified as mediators of Sema3A signaling and neuronal differentiation. Much has been learned about the mechanism by which CRMPs regulate cellular responses to Sema3A.The secreted protein Sema3A (collapsin-1) was the first identified vertebrate semaphorin. Sema3A acts primarily as...
| Keywords: | Sema3a, Semaphorin-D, Semaphorin-3A, Semaphorin III |
| Origin: | mouse |
| MW: | 86.6 kD |
From 551.00€
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Serpin F1/PEDF, His, Mouse
Item number: GSC-Z06345-100
Pigment epithelium-derived factor (PEDF) is an important antiangiogenic and antitumorigenic factor in a variety of cancer forms, including pancreatic cancer. PEDF is mainly secreted as a soluble monomeric glycoprotein. In human pancreatic cancer PEDF levels are decreased, both in the tissue and serum. The decrease...
| Keywords: | Caspin, Serpinf1, Serpin F1, Stromal cell-derived factor 3, Pigment epithelium-derived factor |
| Origin: | mouse |
| MW: | 45.4 kD |
From 403.00€
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Siglec-4a/MAG, His, Mouse
Item number: GSC-Z06352-100
Siglec-4a, also known as Myelin-Associated Glycoprotein (MAG), is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to...
| Keywords: | Mag, Siglec-4a, Myelin-associated glycoprotein |
| Origin: | mouse |
| MW: | 56 kD |
From 403.00€
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Siglec-5/CD170, His, Mouse
Item number: GSC-Z06353-100
Interactions between endothelial selectins and the leukocyte counter-receptor PSGL1 mediates leukocyte recruitment to inflammation sites. PSGL1 is highly sialylated, making it a potential ligand for Siglec-5, a leukocyte-receptor that recognizes sialic acid structures. Binding assays using soluble Siglec-5 variants...
| Keywords: | Siglec5, Sialic acid-binding Ig-like lectin F, Sialic acid-binding Ig-like lectin 5 |
| Origin: | mouse |
| MW: | 46.8 kD |
From 524.00€
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TFPI-2, His, Mouse
Item number: GSC-Z06368-100
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Moreover, in sputum from cystic fibrosis patients TFPI-2 C-terminal fragments are generated and found...
| Keywords: | Tfpi2, Tissue factor pathway inhibitor 2 |
| Origin: | mouse |
| MW: | 24.87 kD |
From 578.00€
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TGF-alpha hFc Chimera, Mouse
Item number: GSC-Z06369-100
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) and of nonsyndromic cleft palate only (NS-CPO). Biologic support for a role of TGFA arises from its presence at high levels in the epithelial tissue of the...
| Keywords: | Tgfa, Protransforming growth factor alpha |
| Origin: | mouse |
| MW: | 32.9 kD |
From 457.00€
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Thyroid Peroxidase, His, Mouse
Item number: GSC-Z06371-100
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT)...
| Keywords: | Tpo, Thyroid peroxidase |
| Origin: | mouse |
| MW: | 90.6 kD |
From 497.00€
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