Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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TIE1, His, Human
Item number: GSC-Z05879-100
TIE1 is a cell surface protein expressed in endothelial cells. Involved in angiogenesis and lymphangiogenesis, including morphogenesis of lymphatic valves, TIE1 is important for lymphatic system functional integrity.
| Keywords: | TIE1, Tyrosine-protein kinase receptor Tie-1 |
| Origin: | human |
| MW: | 80.93 kD |
From 524.00€
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TNFR2/CD120b/TNFRSF1B mFc Chimera, Human
Item number: GSC-Z05896-100
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for...
| Keywords: | p75, TNFRSF1B, p80 TNF-alpha receptor, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, Tumor... |
| Origin: | human |
| MW: | 51.5 kD |
From 403.00€
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TNFRSF11A/Rank hFc Chimera, Human
Item number: GSC-Z05897-100
TNFRSF11A, also known as receptor activator of NF-kappaB (RANK), activates several signaling pathways, such as NF-kappaB, JNK, ERK, p38alpha, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the...
| Keywords: | TNFRSF11A, Receptor activator of NF-KB, Osteoclast differentiation factor receptor, Tumor necrosis factor receptor... |
| Origin: | human |
| MW: | 46.85 kD |
From 524.00€
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TNFRSF11B, His, Human
Item number: GSC-Z05898-100
Osteoprotegerin (OPG) is a key regulator in bone metabolism, that also has effect in vascular system. Studies suggest that osteoprotegerin is a critical arterial calcification inhibitor, and is released by endothelial cells as a protective mechanism for their survival in certain pathological conditions, such as...
| Keywords: | TNFRSF11B, Osteoprotegerin, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B |
| Origin: | human |
| MW: | 44.71 kD |
From 497.00€
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TNFRSF12A/TWEAKR hFc Chimera, Human
Item number: GSC-Z05899-100
Thyroid cancer (TC) is the most well-known endocrine neoplasia as well as a common malignant tumor in the head and neck.TNFRSF12A expression may be a potential useful prognostic molecular biomarker of bad survival in thyroid cancer, in addition, PPAR signaling pathway, insulin signaling pathway, mTOR signaling...
| Keywords: | TNFRSF12A, Tweak-receptor, Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible... |
| Origin: | human |
| MW: | 32.9 kD |
From 349.00€
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Transthyretin/Prealbumin, His, Human
Item number: GSC-Z05920-100
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known, however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial...
| Keywords: | TTR, TBPA, ATTR, Prealbumin, Transthyretin |
| Origin: | human |
| MW: | 14.9 kD |
From 403.00€
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TREM1, His, Human
Item number: GSC-Z05921-100
TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear.
| Keywords: | TREM1, Triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells 1 |
| Origin: | human |
| MW: | 21.4 kD |
From 524.00€
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TREM2 hFc Chimera, Human
Item number: GSC-Z05922-100
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail....
| Keywords: | TREM2, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2 |
| Origin: | human |
| MW: | 44.2 kD |
From 336.00€
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TREM2, His, Human
Item number: GSC-Z05923-100
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail....
| Keywords: | TREM2, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2 |
| Origin: | human |
| MW: | 18.5 kD |
From 524.00€
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TREML2/TLT-2, His, Human
Item number: GSC-Z05924-100
As an important family member of triggering receptor expressed on myeloid cells (TREM), TREM-like transcript 2 gene (TREML2) locates on human chromosome 6p21.1, a newly-identified hot zone for AD susceptibility, and encodes atransmembrane immune receptor. Emerging evidence implied a potential role of TREML2 in the...
| Keywords: | TREML2, Trem-like transcript 2 protein, Triggering receptor expressed on myeloid cells-like protein 2 |
| Origin: | human |
| MW: | 28.2 kD |
From 551.00€
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TRIB3, GST, Human
Item number: GSC-Z05925-100
Tribbles homolog 3 (TRIB3) is a mammalian gene that is upregulated in response to several types of cell death-inducing cellular stress. The TRIB3 protein is a pseudokinase, a protein kinase-like scaffold with impaired catalytic activity.
| Keywords: | SINK, TRIB3, Tribbles homolog 3, p65-interacting inhibitor of NF-kappa-B, Neuronal cell death-inducible putative kinase |
| Origin: | human |
| MW: | 66.14 kD |
From 497.00€
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ULBP-2 hFc Chimera, Human
Item number: GSC-Z05939-100
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
| Keywords: | ULBP2, ALCAN-alpha, NKG2D ligand 2, UL16-binding protein 2, Retinoic acid early transcript 1H |
| Origin: | human |
| MW: | 48.4 kD |
From 524.00€
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