Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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IL-18BP hFc Chimera, Human
Item number: GSC-Z05453-100
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy...
| Keywords: | IL18BP, Tadekinig-alfa, Interleukin-18-binding protein |
| Origin: | human |
| MW: | 44.4 kD |
From 228.00€
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IL-18BP, His, Human
Item number: GSC-Z05454-100
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy...
| Keywords: | IL18BP, Tadekinig-alfa, Interleukin-18-binding protein |
| Origin: | human |
| MW: | 18.7 kD |
From 202.00€
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IL-1RL1/ST2 hFc Chimera, Human
Item number: GSC-Z05467-100
IL1RL1(also known as ST2) is a member of the IL1 receptor family and serves as the receptor for IL-33. The ST2 protein has two isoforms including sST2 and the membrane-bound ST2 receptor, referred to as ST2L. Preclinical studies have demonstrated that binding of IL-33 to ST2L elicits a cardioprotective effect....
| Keywords: | IL1RL1, Protein ST2, Interleukin-1 receptor-like 1 |
| Origin: | human |
| MW: | 61.75 kD |
From 228.00€
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IL-1RL1/ST2, His, Human
Item number: GSC-Z05468-100
IL1RL1(also known as ST2) is a member of the IL1 receptor family and serves as the receptor for IL-33. The ST2 protein has two isoforms including sST2 and the membrane-bound ST2 receptor, referred to as ST2L. Preclinical studies have demonstrated that binding of IL-33 to ST2L elicits a cardioprotective effect....
| Keywords: | IL1RL1, Protein ST2, Interleukin-1 receptor-like 1 |
| Origin: | human |
| MW: | 36 kD |
From 255.00€
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IL-2, Human
Item number: GSC-Z05469-100
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system,...
| Keywords: | IL2, Interleukin-2, T-cell growth factor |
| Origin: | human |
| MW: | 15.41 kD |
From 202.00€
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IL-22, His, Human
Item number: GSC-Z05478-100
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
| Keywords: | IL22, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor |
| Origin: | human |
| MW: | 17.8 kD |
From 497.00€
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IL-23 alpha&IL-12 beta, His, Human
Item number: GSC-Z05481-100
The interleukin (IL)-12 family of cytokines, including IL12 and IL 23, play an important role in driving aberrant Th1 and Th17 immune responses in patients with Crohn's disease (CD). Targeting this pathway has opened new avenues for therapeutic intervention. The balance of proinflammatory cytokines interleukin...
| Keywords: | IL12A, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1, Cytotoxic lymphocyte... |
| Origin: | human |
| MW: | 19.77/34.7 kD |
From 524.00€
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IL-23 alpha&IL-12 beta, His & Avi, Human&Mouse
Item number: GSC-Z05482-100
Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common beta subunit p40 and the specific cytokine alpha subunit p35 and p19, respectively. IL-12 signals via the IL-12Rbeta1·IL-12Rbeta2 receptor complex, and IL-23 uses also IL-12Rbeta1 but engages IL-23R as...
| Keywords: | IL12A, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1, Cytotoxic lymphocyte... |
| MW: | 21.7/35.8 kD |
From 793.00€
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IL-23 P19/IL-23A hFc Chimera, Human
Item number: GSC-Z05483-100
IL-23 is a heterodimeric cytokine composed of a unique p19 subunit and a common p40 subunit is shared with IL-12. IL-23 promotes the inflammatory response by inducing the expansion of CD4(+) cells producing IL-17.
| Keywords: | IL23A, Interleukin-23 subunit p19, Interleukin-23 subunit alpha |
| Origin: | human |
| MW: | 45.43 kD |
From 497.00€
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IL-31, His, Human
Item number: GSC-Z05496-100
Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus. While histamine and neuropeptides have previously been ascribed to play a role in itch that accompanies these diseases, recent evidence suggests that the...
| Keywords: | IL31, Interleukin-31 |
| Origin: | human |
| MW: | 16.9 kD |
From 524.00€
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IL-31 RA hFc Chimera, Human
Item number: GSC-Z05498-100
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMRbeta). OSMRbeta is...
| Keywords: | GLM-R, IL31RA, ZcytoR17, Cytokine receptor-like 3, Gp130-like monocyte receptor, Interleukin-31 receptor subunit alpha |
| Origin: | human |
| MW: | 83.8 kD |
From 524.00€
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IL-33, Human
Item number: GSC-Z05499-100
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33,...
| Keywords: | IL33, Interleukin-33, Interleukin-1 family member 11, Nuclear factor from high endothelial venules |
| Origin: | human |
| MW: | 18 kD |
From 578.00€
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