Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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ICAM-3/CD50, His, Human
Item number: GSC-Z05391-100
ICAM-3 interacts with LFA1, and is involved in the intercellular adhesion of leukocytes as well as in the mainenance of cell survival. ICAM-3 expression induces cancer cell proliferation, and an increase in ICAM-3 expression can contribute to cancer progression.
| Keywords: | ICAM3, CDw50, ICAM-R, Intercellular adhesion molecule 3 |
| Origin: | human |
| MW: | 50.54 kD |
From 457.00€
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IDH1, His, Human
Item number: GSC-Z05396-100
Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to alpha-ketoglutarate (alpha-KG). Genetic gain-of-function mutations in IDH1 and IDH2 confer a neomorphic activity that allow reduction of alpha -KG to (R)-2- hydroxyglutarate, the accumulation of which results in the development of...
| Keywords: | IDPc, IDH1, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, Cytosolic NADP-isocitrate dehydrogenase, Isocitrate... |
| Origin: | human |
| MW: | 47.35 kD |
From 457.00€
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IGF2R, His & Avi, Human
Item number: GSC-Z05407-100
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
| Keywords: | IGF2R, M6P/IGF2 receptor, 300 kDa mannose 6-phosphate receptor, Insulin-like growth factor 2 receptor, Insulin-like growth... |
| Origin: | human |
| MW: | 164.9 kD |
From 524.00€
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IGFBP-2, His, Human
Item number: GSC-Z05408-100
Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a developmentally regulated gene that is highly expressed in embryonic and fetal tissues and markedly...
| Keywords: | IGFBP2, Insulin-like growth factor-binding protein 2 |
| Origin: | human |
| MW: | 32.5 kD |
From 457.00€
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IGFBP-3, His, Human
Item number: GSC-Z05409-100
Insulin-like growth factor binding protein-3 (IGFBP-3) is a p53 tumor suppressor-regulated protein and a major carrier for IGFs in circulation. Among six high-affinity IGFBPs, which are IGFBP-1 through 6, IGFBP-3 is the most extensively investigated IGFBP species with respect to its IGF/IGF-I receptor...
| Keywords: | IGFBP3, Insulin-like growth factor-binding protein 3 |
| Origin: | human |
| MW: | 29.8 kD |
From 336.00€
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IL-12, His & Avi, Human
Item number: GSC-Z05429-100
Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.
| Keywords: | IL12A, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1, Cytotoxic lymphocyte... |
| Origin: | human |
| MW: | 34.7/25.5 kD |
From 887.00€
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IL-12 R beta 1/CD212, His, Human
Item number: GSC-Z05431-100
Human IL12RB1 is an autosomal gene that is essential for mycobacterial disease resistance and T cell differentiation. Lung and T cell IL12RB1 expression is allele-biased, and the extent to which cells express one IL12RB1 allele is unaffected by activation. Furthermore following its expression the IL12RB1 pre-mRNA is...
| Keywords: | IL12RB1, IL-12 receptor beta component, Interleukin-12 receptor subunit beta-1 |
| Origin: | human |
| MW: | 58.2 kD |
From 349.00€
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IL-12B/p40/NKSF2, His, Human
Item number: GSC-Z05432-100
Interleukin (IL)-12B, which encodes the p40 subunit common to IL-12 and IL-23, as one of the genes for which expression in fibroblast-like synoviocytes from patients with rheumatoid arthritis (RA-FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin-related...
| Keywords: | IL12B, IL-12 subunit p40, Interleukin-12 subunit beta, NK cell stimulatory factor chain 2, Cytotoxic lymphocyte maturation... |
| Origin: | human |
| MW: | 35.8 kD |
From 457.00€
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IL-13, Human
Item number: GSC-Z05433-100
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine...
| Keywords: | IL13, Interleukin-13 |
| Origin: | human |
| MW: | 12.35 kD |
From 457.00€
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IL-13 hFc Chimera, Human
Item number: GSC-Z05434-100
Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine...
| Keywords: | IL13, Interleukin-13 |
| Origin: | human |
| MW: | 39.6 kD |
From 403.00€
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IL-18 R1/CD218a hFc Chimera, Human
Item number: GSC-Z05451-100
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-gamma production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon...
| Keywords: | IL18R1, CDw218a, Interleukin-18 receptor 1, IL1 receptor-related protein, Interleukin-18 receptor alpha, CD218... |
| Origin: | human |
| MW: | 62.52 kD |
From 228.00€
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IL-18 R1/CD218a, His & Avi, Human
Item number: GSC-Z05452-100
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-gamma production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon...
| Keywords: | IL18R1, CDw218a, Interleukin-18 receptor 1, IL1 receptor-related protein, Interleukin-18 receptor alpha, CD218... |
| Origin: | human |
| MW: | 38.8 kD |
From 228.00€
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