Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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MMP-8, His, Cynomolgus
Item number: GSC-Z04874-100
Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in...
| Keywords: | MMP8 |
| Origin: | cynomolgus |
| MW: | 52.27 kD |
From 524.00€
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NKG2C&CD94, His & Flag, Cynomolgus
Item number: GSC-Z04880-100
NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the...
| Keywords: | nkg2C |
| Origin: | cynomolgus |
| MW: | 16.4/18.3 kD |
From 524.00€
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NOGOR, His, Cynomolgus
Item number: GSC-Z04884-100
NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients...
| Keywords: | RTN4R, Nogo receptor, Nogo-66 receptor, Reticulon-4 receptor |
| Origin: | cynomolgus |
| MW: | 46.34 kD |
From 524.00€
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PCSK9, His, Cynomolgus
Item number: GSC-Z04891-100
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.The first two PCSK9 inhibitors, alirocumab and evolocumab, were approved as once every two week injections, by the U.S. Food and Drug Administration in 2015 for lowering LDL-particle concentrations...
| Keywords: | PCSK9, Proprotein convertase 9, Subtilisin/kexin-like protease PC9, Proprotein convertase subtilisin/kexin type 9 |
| Origin: | cynomolgus |
| MW: | 59/14 kD |
From 457.00€
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PD-L1/B7-H1 hFc Chimera, Cynomolgus
Item number: GSC-Z04896-100
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune...
| Keywords: | CD274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Origin: | cynomolgus |
| MW: | 52 kD |
From 255.00€
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PD-L2/B7-DC, His, Cynomolgus
Item number: GSC-Z04897-100
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong...
| Keywords: | PDCD1LG2, Butyrophilin B7-DC, Programmed cell death 1 ligand 2 |
| Origin: | cynomolgus |
| MW: | 23.73 kD |
From 457.00€
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PLAU/uPA (active form), His, Cynomolgus
Item number: GSC-Z04898-100
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
| Keywords: | PLAU, Urokinase-type plasminogen activator |
| Origin: | cynomolgus |
| MW: | 47.23 kD |
From 524.00€
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PRLR, His, Cynomolgus
Item number: GSC-Z04899-100
Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target....
| Keywords: | PRLR, Prolactin receptor |
| Origin: | cynomolgus |
| MW: | 25.75 kD |
From 524.00€
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PS20, His, Cynomolgus
Item number: GSC-Z04900-100
The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection...
| Keywords: | WFDC1, ps20 growth inhibitor, Prostate stromal protein ps20, WAP four-disulfide core domain protein 1 |
| Origin: | cynomolgus |
| MW: | 18.77 kD |
From 524.00€
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PVRIG, His, Cynomolgus
Item number: GSC-Z04904-100
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that...
| Keywords: | PVR related immunoglobulin domain containing |
| Origin: | cynomolgus |
| MW: | 14.78 kD |
From 551.00€
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PVRIG hFc Chimera, Cynomolgus
Item number: GSC-Z04905-100
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that...
| Keywords: | PVR related immunoglobulin domain containing |
| Origin: | cynomolgus |
| MW: | 40.3 kD |
From 551.00€
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SERPINF2/A2AP, His, Cynomolgus
Item number: GSC-Z04910-100
Large-pool solvent/detergent (SD) plasma for transfusion exhibits reduced alpha 2-antiplasmin (alpha2-AP, SERPINF2) functional activity. The reason for the loss of alpha2-AP has not been described and could be due to the SD incubation itself and/or to the processing steps implemented to remove the solvent and the...
| Keywords: | SERPINF2 |
| Origin: | cynomolgus |
| MW: | 52.83 kD |
From 524.00€
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