Products from GenScript

GenScript

GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.

More information at: www.genscript.com

285 from 323 pages
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IFN alpha/beta R2[Biotin], His & Avi, Human
IFN alpha/beta R2[Biotin], His & Avi, Human

Item number: GSC-Z04481-100

Although interferon (IFN)-alpha is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-alpha-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is...
Keywords: IFNGR2, Interferon gamma receptor 2, Interferon gamma transducer 1, Interferon gamma receptor beta-chain, Interferon gamma...
Origin: human
MW: 27.66 kD
From 887.00€ *
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IFN gamma/IFNG[Biotin], His & Avi, Human
IFN gamma/IFNG[Biotin], His & Avi, Human

Item number: GSC-Z04482-100

Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates...
Keywords: IFNG, Interferon gamma, Immune interferon
Origin: human
MW: 19.1 kD
From 887.00€ *
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IgE[Biotin], His & Avi, Human
IgE[Biotin], His & Avi, Human

Item number: GSC-Z04483-100

Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcepsilonRI and CD23 (FcepsilonRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been...
Keywords: IGHE, Ig epsilon chain C region, Ig epsilon chain C region ND, Immunoglobulin heavy constant epsilon
Origin: human
MW: 27.8 kD
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IGF1R/CD221[Biotin], His & Avi, Human
IGF1R/CD221[Biotin], His & Avi, Human

Item number: GSC-Z04484-100

The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for...
Keywords: IGF1R, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor
Origin: human
MW: 105.8/23 kD
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IL-10 R alpha[Biotin], His & Avi, Human
IL-10 R alpha[Biotin], His & Avi, Human

Item number: GSC-Z04490-100

The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many inflammatory disorders in livestock, including Johne's disease (JD). JD is a chronic...
Keywords: IL10RA, CDw210a, Interleukin-10 receptor subunit 1, Interleukin-10 receptor subunit alpha
Origin: human
MW: 27 kD
From 887.00€ *
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IL-12[Biotin], His & Avi, Human
IL-12[Biotin], His & Avi, Human

Item number: GSC-Z04491-100

Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.
Keywords: IL12A, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1, Cytotoxic lymphocyte...
Origin: human
MW: 34.7/25.5 kD
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IL-13[Biotin], His & Avi, Human
IL-13[Biotin], His & Avi, Human

Item number: GSC-Z04492-100

Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine...
Keywords: IL13, Interleukin-13
Origin: human
MW: 15.3 kD
From 887.00€ *
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IL-13Ra1[Biotin], His & Avi, Human
IL-13Ra1[Biotin], His & Avi, Human

Item number: GSC-Z04493-100

Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding...
Keywords: IL13RA1, Cancer/testis antigen 19, Interleukin-13 receptor subunit alpha-1
Origin: human
MW: 39.5 kD
From 887.00€ *
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IL-15RA&IL-15 [Biotin], His, Human
IL-15RA&IL-15 [Biotin], His, Human

Item number: GSC-Z04494-100

Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development.
Keywords: IL15RA, Interleukin-15 receptor subunit alpha
Origin: human
MW: 23.8 kD
From 887.00€ *
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IL-17R alpha/CD217 hFc Chimera[Biotin], Avi, Human
IL-17R alpha/CD217 hFc Chimera[Biotin], Avi, Human

Item number: GSC-Z04500-100

Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 R) which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution, and has been...
Keywords: IL17RA, CDw217, Interleukin-17 receptor A
Origin: human
MW: 61.8 kD
From 887.00€ *
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IL-18BP[Biotin], His & Avi, Human
IL-18BP[Biotin], His & Avi, Human

Item number: GSC-Z04504-100

Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy...
Keywords: IL18BP, Tadekinig-alfa, Interleukin-18-binding protein
Origin: human
MW: 20.5 kD
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IL-2[Biotin], His & Avi, Human
IL-2[Biotin], His & Avi, Human

Item number: GSC-Z04506-100

Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system,...
Keywords: IL2, Interleukin-2, T-cell growth factor
Origin: human
MW: 18.32 kD
From 887.00€ *
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285 from 323 pages