Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
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IL-17R alpha/CD217 hFc Chimera, Mouse
Item number: GSC-Z04341-100
Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 R) which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution, and has been...
| Keywords: | Il17ra, Interleukin-17 receptor A |
| Origin: | mouse |
| MW: | 60.1 kD |
From 376.00€
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NKG2D/CD314 hFc Chimera, Mouse
Item number: GSC-Z04345-100
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma delta T cells, NK cells and NKT...
| Keywords: | Klrk1, NK cell receptor D, NKG2-D-activating NK receptor, NKG2-D type II integral membrane protein, Killer cell... |
| Origin: | mouse |
| MW: | 43.7 kD |
From 457.00€
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CD28, His, Rat
Item number: GSC-Z04350-100
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
| Keywords: | Cd28, T-cell-specific surface glycoprotein CD28 |
| Origin: | rat |
| MW: | 16.66 kD |
From 457.00€
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Alkaline Phosphatase (Placental type) /ALPP [Biotin],...
Item number: GSC-Z04357-100
Alkaline phosphatase can be considered 'our favorite enzyme' for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the...
| Keywords: | ALPP, Alkaline phosphatase |
| Origin: | cynomolgus |
| MW: | 53.69 kD |
From 887.00€
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BTN3A1/CD277[Biotin], His & Avi, Cynomolgus
Item number: GSC-Z04359-100
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A1 controls activation of human Vgamma9/Vdelta2 T cells by direct or indirect presentation of self and nonself phosphoantigens (pAg).
| Keywords: | BTN3A1, RING-type E3 ubiquitin transferase |
| Origin: | cynomolgus |
| MW: | 26.5 kD |
From 887.00€
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IL-10 R alpha [Biotin], His, Cynomolgus
Item number: GSC-Z04370-100
The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pathogenesis of many inflammatory disorders in livestock, including Johne's disease (JD). JD is a chronic...
| Keywords: | IL10RA, CDw210a, Interleukin-10 receptor subunit 1, Interleukin-10 receptor subunit alpha |
| Origin: | cynomolgus |
| MW: | 25.34 kD |
From 887.00€
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Siglec-10[Biotin], His & Avi, Cynomolgus
Item number: GSC-Z04376-100
Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that...
| Keywords: | SIGLEC10 |
| Origin: | cynomolgus |
| MW: | 61.71 kD |
From 887.00€
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Siglec-15/CD33L3[Biotin], His & Avi, Cynomolgus
Item number: GSC-Z04377-100
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential...
| Keywords: | SIGLEC15 |
| Origin: | cynomolgus |
| MW: | 29.2 kD |
From 887.00€
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TSLP [Biotin], His, Cynomolgus
Item number: GSC-Z04378-100
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c...
| Keywords: | TSLP |
| Origin: | cynomolgus |
| MW: | 16.3 kD |
From 887.00€
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FcRn[Biotin], His & Avi, Cynomolgus/Rhesus macaque
Item number: GSC-Z04379-100
The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein...
| Keywords: | FCGRT, Neonatal Fc receptor, IgG receptor FcRn large subunit p51, IgG Fc fragment receptor transporter alpha chain |
| Origin: | cynomolgus, rhesus macaque |
| MW: | 46.5 kD |
From 887.00€
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PD-L1/B7-H1 [Biotin], His, Cynomolgus/Rhesus macaque
Item number: GSC-Z04381-100
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune...
| Keywords: | CD274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Origin: | cynomolgus, rhesus macaque |
| MW: | 26 kD |
From 887.00€
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4-1BB/TNFRSF9 hFc Chimera[Biotin], Avi, Human
Item number: GSC-Z04384-100
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural...
| Keywords: | CDw137, TNFRSF9, T-cell antigen ILA, 4-1BB ligand receptor, T-cell antigen 4-1BB homolog, Tumor necrosis factor receptor... |
| Origin: | human |
| MW: | 45.7 kD |
From 887.00€
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