Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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LILRB1/CD85j/ILT2 hFc Chimera, Rhesus macaque
Item number: GSC-Z06448-100
LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory...
| Keywords: | Ig-like domain-containing protein |
| Origin: | rhesus macaque |
| MW: | 74.5 kD |
From 457.00€
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Siglec-2/CD22, His, Rhesus macaque
Item number: GSC-Z06449-100
CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling....
| Keywords: | CD22, B-cell receptor CD22, Sialic acid-binding Ig-like lectin 2 |
| Origin: | rhesus macaque |
| MW: | 76.14 kD |
From 457.00€
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HLA-G&B2M&Peptide (RIIPRHLQL) Monomer[Biotin], His & Avi,...
Item number: GSC-Z06458-100
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or...
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | cynomolgus |
| MW: | 50.6 kD |
From 685.00€
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HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer[Biotin], His &...
Item number: GSC-Z06460-100
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting...
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 50.4 kD |
From 685.00€
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HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Monomer[Biotin], His...
Item number: GSC-Z06461-100
Human cytomegalovirus (CMV) is one of the major causes of severe complications in immunocompromised patients, such as recipients of hematopoietic cells, solid organ transplantation, and HIV-infected individuals. CMV is also a major pathogen in congenital infection. It can cause life-threatening diseases and severe...
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 50.35 kD |
From 685.00€
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HLA-A*02:01&B2M&CMVpp65 (NLVPMVATV) Monomer[Biotin], His...
Item number: GSC-Z06462-100
Human cytomegalovirus (CMV), a beta-herpes virus with a double-stranded DNA, infects a wide variety of cells and establishes latency in the host. CMVpp65, a tegument protein of the herpes virus CMV, is the main viral antigen found in peripheral blood mononuclear cells (PBMCs) after viral infection and may activate...
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 35.6/1.9 kD |
From 685.00€
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HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer[Biotin], His &...
Item number: GSC-Z06468-100
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer...
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 50.3 kD |
From 685.00€
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HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer[Biotin], His...
Item number: GSC-Z06469-100
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 50.5 kD |
From 685.00€
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HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer[Biotin], His...
Item number: GSC-Z06470-100
MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of...
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 50.44 kD |
From 685.00€
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HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer[Biotin], His &...
Item number: GSC-Z06481-100
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 50.6 kD |
From 685.00€
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HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer[Biotin], His &...
Item number: GSC-Z06482-100
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 50.4 kD |
From 685.00€
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HLA-A*03:01&B2M&KRAS G12V (VVGAVGVGK) Monomer[Biotin],...
Item number: GSC-Z06487-100
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and...
| Keywords: | B2M, Beta-2-microglobulin |
| Origin: | human |
| MW: | 50.09 kD |
From 685.00€
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