Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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PD-1/PDCD1 hFc Chimera, Mouse
Item number: GSC-Z06299-100
Programmed cell death protein 1, also known as PD-1 and CD279, is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
| Keywords: | Pdcd1, Programmed cell death protein 1 |
| Origin: | mouse |
| MW: | 42.9 kD |
From 457.00€
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PILRA, His, Mouse
Item number: GSC-Z06310-100
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance, Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface...
| Keywords: | Pilra, Cell surface receptor FDF03, Inhibitory receptor PILR-alpha, Paired immunoglobulin-like type 2 receptor alpha |
| Origin: | mouse |
| MW: | 19.71 kD |
From 457.00€
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PILRA hFc Chimera, Mouse
Item number: GSC-Z06311-100
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance, Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface...
| Keywords: | Pilra, Cell surface receptor FDF03, Inhibitory receptor PILR-alpha, Paired immunoglobulin-like type 2 receptor alpha |
| Origin: | mouse |
| MW: | 45.4 kD |
From 457.00€
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PLAU/uPA, His & Avi, Mouse
Item number: GSC-Z06316-100
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
| Keywords: | Plau, Urokinase-type plasminogen activator |
| Origin: | mouse |
| MW: | 49 kD |
From 403.00€
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PSGL-1, His, Mouse
Item number: GSC-Z06327-100
P-selectin glycoprotein ligand-1 (PSGL-1) has long been studied as an adhesion molecule involved in immune cell trafficking and is recognized as a regulator of many facets of immune responses by myeloid cells. PSGL-1 also regulates T cell migration during homeostasis and inflammatory settings.
| Keywords: | Selplg, Selectin P ligand, P-selectin glycoprotein ligand 1 |
| Origin: | mouse |
| MW: | 28.74 kD |
From 524.00€
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PVRIG hFc Chimera, Avi, Mouse
Item number: GSC-Z06332-100
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.
| Keywords: | Nectin2, Nectin-2, Poliovirus receptor homolog, Herpes virus entry mediator B, Nectin cell adhesion molecule 2, Murine... |
| Origin: | mouse |
| MW: | 42.7 kD |
From 524.00€
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RNF43 hFc Chimera, Mouse
Item number: GSC-Z06337-100
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/beta-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the...
| Keywords: | Rnf43, RING finger protein 43, E3 ubiquitin-protein ligase RNF43, RING-type E3 ubiquitin transferase RNF43 |
| Origin: | mouse |
| MW: | 45.6 kD |
From 457.00€
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ROBO4, His, Mouse
Item number: GSC-Z06338-100
Roundabout4 (Robo4) is a transmembrane receptor that belongs to the Roundabout (Robo) family of axon guidance molecules. Robo4 is an endothelial-specific receptor that participates in endothelial cell migration, proliferation, and angiogenesis and the maintenance of vasculature homeostasis. Robo4 is a promising and...
| Keywords: | Robo4, Roundabout homolog 4 |
| Origin: | mouse |
| MW: | 50.3 kD |
From 484.00€
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S100A9/MRP14, His, Mouse
Item number: GSC-Z06339-100
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor,...
| Keywords: | S100a9, Calgranulin-B, Protein S100-A9, S100 calcium-binding protein A9, Leukocyte L1 complex heavy chain, Migration... |
| Origin: | mouse |
| MW: | 14.1 kD |
From 524.00€
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SELL/CD62L, His, Mouse
Item number: GSC-Z06340-100
L-selectin (CD62L) is a type-I transmembrane glycoprotein and cell adhesion molecule that is expressed on most circulating leukocytes. Since its identification in 1983, L-selectin has been extensively characterized as a tethering/rolling receptor. There is now mounting evidence in the literature to suggest that...
| Keywords: | Sell, L-selectin, Lymphocyte antigen 22, Lymph node homing receptor, Leukocyte adhesion molecule 1, Lymphocyte surface... |
| Origin: | mouse |
| MW: | 34.2 kD |
From 457.00€
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SEMA7A, His, Mouse
Item number: GSC-Z06343-100
Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic rats, which may be related to neuroinflammation. Sema7A promotes the inflammatory cytokines...
| Keywords: | Sema7a, Semaphorin-L, Semaphorin-7A, Semaphorin-K1 |
| Origin: | mouse |
| MW: | 69.5 kD |
From 363.00€
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Semaphorin 4D/SEMA4D/CD100, His, Mouse
Item number: GSC-Z06344-100
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression.
| Keywords: | Sema4d, M-Sema G, Semaphorin-J, Semaphorin-4D, Semaphorin-C-like 2 |
| Origin: | mouse |
| MW: | 79.87 kD |
From 497.00€
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