Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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TNFRSF19 hFc Chimera, Human
Item number: GSC-Z05901-100
A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for nasopharyngeal carcinoma and other cancers, functions as a potent inhibitor of the TGFbeta...
| Keywords: | TRADE, TNFRSF19, Toxicity and JNK inducer, Tumor necrosis factor receptor superfamily member 19 |
| Origin: | human |
| MW: | 42.22 kD |
From 457.00€
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TNFSF12/TWEAK hFc Chimera, Human
Item number: GSC-Z05902-100
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumulating evidence has shown that TWEAK binding to the receptor factor-inducible 14 (Fn14) participates in diverse pathologic processes including cell...
| Keywords: | TNFSF12, APO3 ligand, TNF-related weak inducer of apoptosis, Tumor necrosis factor ligand superfamily member 12 |
| Origin: | human |
| MW: | 49.62 kD |
From 497.00€
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TPBG/5T4 hFc Chimera, Human
Item number: GSC-Z05907-100
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs.
| Keywords: | M6P1, TPBG, 5T4 oncofetal antigen, Trophoblast glycoprotein, Wnt-activated inhibitory factor 1, 5T4 oncofetal trophoblast... |
| Origin: | human |
| MW: | 62.08 kD |
From 524.00€
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TPBG/5T4, His & Avi, Human
Item number: GSC-Z05908-100
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs.
| Keywords: | M6P1, TPBG, 5T4 oncofetal antigen, Trophoblast glycoprotein, Wnt-activated inhibitory factor 1, 5T4 oncofetal trophoblast... |
| Origin: | human |
| MW: | 38.2 kD |
From 524.00€
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TPM1, His, Human
Item number: GSC-Z05909-100
Tropomyosin-1 (TPM1), a widely expressed actin-binding protein, is downregulated in many tumors and associated with cancer progression. TPM1 overexpression in RCC cell lines can induce tumor cell apoptosis via the p53-mediated mitochondrial pathway. Further studies are needed to fully elucidate the potential of TPM1...
| Keywords: | TPM1, Tropomyosin-1, Alpha-tropomyosin, Tropomyosin alpha-1 chain |
| Origin: | human |
| MW: | 34.26 kD |
From 497.00€
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TRAIL R2/DR5/TNFRSF10B, His & Avi, Human
Item number: GSC-Z05913-100
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates...
| Keywords: | TNFRSF10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily... |
| Origin: | human |
| MW: | 17.2 kD |
From 363.00€
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TRAIL R4/TNFRSF10D, His & Avi, Human
Item number: GSC-Z05914-100
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in...
| Keywords: | TNFRSF10D, Decoy receptor 2, TRAIL receptor with a truncated death domain, TNF-related apoptosis-inducing ligand receptor... |
| Origin: | human |
| MW: | 19.4 kD |
From 524.00€
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TRAIL/TNFRSF10, Human
Item number: GSC-Z05916-100
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the development of TRAIL-based...
| Keywords: | TNFSF10, Apo-2 ligand, TNF-related apoptosis-inducing ligand, Tumor necrosis factor ligand superfamily member 10 |
| Origin: | human |
| MW: | 19.6 kD |
From 524.00€
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TSLPR, His, Human
Item number: GSC-Z05931-100
TSLP is an epithelial cell-derived cytokine synthesized in response to various stimuli, including protease allergens and microorganisms like viruses and bacteria. Biological functions of TSLP require heterodimer formation between the TSLP receptor (TSLPR) and IL-7 receptor-alpha, which polarize dendritic cells to...
| Keywords: | CRLF2, IL-XR, Cytokine receptor-like 2, Cytokine receptor-like factor 2, Thymic stromal lymphopoietin protein receptor |
| Origin: | human |
| MW: | 25.1 kD |
From 497.00€
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TSLPR hFc Chimera, Human
Item number: GSC-Z05932-100
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
| Keywords: | CRLF2, IL-XR, Cytokine receptor-like 2, Cytokine receptor-like factor 2, Thymic stromal lymphopoietin protein receptor |
| Origin: | human |
| MW: | 50.8 kD |
From 497.00€
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UBASH3B/STS1, His, Human
Item number: GSC-Z05937-100
UBASH3/STS/TULA is a novel two-member family, which exerts several key regulatory effects in multiple cell types. UBASH3B/STS-1/TULA-2 is a highly active protein tyrosine phosphatase, its major target appears to be a specific regulatory site of protein tyrosine kinases of the Syk family, dephosphorylation of which...
| Keywords: | UBASH3B, T-cell ubiquitin ligand 2, Cbl-interacting protein p70, Tyrosine-protein phosphatase STS1/TULA2, Suppressor of... |
| Origin: | human |
| MW: | 31.88 kD |
From 497.00€
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ULBP-1, His & Avi, Human
Item number: GSC-Z05938-100
ULBP-1, or UL16-binding protein 1, is a protein that plays a significant role in the immune system, particularly in the recognition and elimination of abnormal cells, such as those found in cancer. It is a ligand for the NKG2D receptor, which is expressed on the surface of natural killer (NK) cells and certain T...
| Keywords: | ULBP1, ALCAN-beta, NKG2D ligand 1, UL16-binding protein 1, Retinoic acid early transcript 1I |
| Origin: | human |
| MW: | 25.2 kD |
From 524.00€
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