Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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OX40/TNFRSF4/CD134, His & Avi, Human
Item number: GSC-Z05728-100
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation, its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following...
| Keywords: | TNFRSF4, ACT35 antigen, OX40L receptor, Tumor necrosis factor receptor superfamily member 4, TAX... |
| Origin: | human |
| MW: | 23.2 kD |
From 605.00€
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PADI4, His, Human
Item number: GSC-Z05729-100
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has...
| Keywords: | PADI4, HL-60 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type-4, Protein-arginine deiminase type IV |
| Origin: | human |
| MW: | 76.6 kD |
From 887.00€
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PDGF R alpha/PDGFRA, His & Avi, Human
Item number: GSC-Z05737-100
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two...
| Keywords: | PDGFRA, CD140a antigen, CD140 antigen-like family member A, Platelet-derived growth factor receptor 2, Platelet-derived... |
| Origin: | human |
| MW: | 59.2 kD |
From 309.00€
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PD-L1/B7-H1, Llama Fc Chimera, Human
Item number: GSC-Z05740-100
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune...
| Keywords: | CD274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Origin: | human |
| MW: | 52.5 kD |
From 524.00€
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PGLYRP1 hFc Chimera, Human
Item number: GSC-Z05750-100
Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFalpha receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either...
| Keywords: | PGLYRP1, Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short |
| Origin: | human |
| MW: | 46.2 kD |
From 497.00€
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PHOSPHO1, His, Human
Item number: GSC-Z05751-100
PHOSPHO1, a phosphoethanolamine/phosphocholine phosphatase, is upregulated in mineralising cells and is thought to be involved in the generation of inorganic phosphate for bone mineralisation.
| Keywords: | PHOSPHO1, Phosphoethanolamine/phosphocholine phosphatase |
| Origin: | human |
| MW: | 30.67 kD |
From 497.00€
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PRL-1/PTP4A1, His, Human
Item number: GSC-Z05765-100
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is a key molecule that activates tyrosine phosphorylation, which is important for cancer progression...
| Keywords: | PTP4A1, PTP(CAAXI), Protein-tyrosine phosphatase 4a1, Protein tyrosine phosphatase type IVA 1, Protein-tyrosine... |
| Origin: | human |
| MW: | 20.56 kD |
From 457.00€
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R spondin 1/RSPO1, His, Human
Item number: GSC-Z05782-100
The R-spondins are members of a superfamily of thrombospondin type 1 repeat (TSR-1)-containing proteins. The prototype member (discovered in 1971) was isolated from platelets that had been stimulated with thrombin, and was therefore designated 'thrombin-sensitive protein.
| Keywords: | RSPO1, R-spondin-1, Roof plate-specific spondin-1 |
| Origin: | human |
| MW: | 27.3 kD |
From 685.00€
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RNF43, His, Human
Item number: GSC-Z05790-100
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/beta-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the...
| Keywords: | RNF43, RING finger protein 43, E3 ubiquitin-protein ligase RNF43, RING-type E3 ubiquitin transferase RNF43 |
| Origin: | human |
| MW: | 20.14 kD |
From 524.00€
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S100A9/MRP14, His, Human
Item number: GSC-Z05797-100
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor,...
| Keywords: | S100A9, Calgranulin-B, Protein S100-A9, Calprotectin L1H subunit, S100 calcium-binding protein A9, Leukocyte L1 complex... |
| Origin: | human |
| MW: | 14.3 kD |
From 403.00€
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SELL/CD62L, His, Human
Item number: GSC-Z05800-100
L-selectin (CD62L) is a type-I transmembrane glycoprotein and cell adhesion molecule that is expressed on most circulating leukocytes. Since its identification in 1983, L-selectin has been extensively characterized as a tethering/rolling receptor. There is now mounting evidence in the literature to suggest that...
| Keywords: | TQ1, SELL, gp90-MEL, L-selectin, Lymph node homing receptor, Leukocyte adhesion molecule 1, Leukocyte surface antigen... |
| Origin: | human |
| MW: | 34.1 kD |
From 457.00€
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SEMA4B, His, Human
Item number: GSC-Z05802-100
Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21....
| Keywords: | SEMA4B, Semaphorin-C, Semaphorin-4B |
| Origin: | human |
| MW: | 75.8 kD |
From 430.00€
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