Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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NKG2A&CD94 hFc Chimera, Flag, Human
Item number: GSC-Z05682-100
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK...
| Keywords: | KLRC1, NK cell receptor A, NKG2-A/B-activating NK receptor, CD159 antigen-like family member A, NKG2-A/NKG2-B type II... |
| Origin: | human |
| MW: | 41.1/17.9 kD |
From 524.00€
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NKG2A&CD94, His & Avi, Flag Human
Item number: GSC-Z05684-100
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK...
| Keywords: | KLRC1, NK cell receptor A, NKG2-A/B-activating NK receptor, CD159 antigen-like family member A, NKG2-A/NKG2-B type II... |
| Origin: | human |
| MW: | 17.9/18.3 kD |
From 524.00€
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NKG2A&CD94 mFc Chimera, Human
Item number: GSC-Z05685-100
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK...
| Keywords: | KP43, KLRD1, NK cell receptor, Natural killer cells antigen CD94, Killer cell lectin-like receptor subfamily D member 1 |
| Origin: | human |
| MW: | 56.9 kD |
From 551.00€
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NKp30/NCR3/CD337 hFc Chimera, Human
Item number: GSC-Z05691-100
NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance,...
| Keywords: | NCR3, Activating natural killer receptor p30, Natural killer cell p30-related protein, Natural cytotoxicity triggering... |
| Origin: | human |
| MW: | 39.8 kD |
From 403.00€
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NKp46/NCR1/CD335, His, Human
Item number: GSC-Z05694-100
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR). These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic...
| Keywords: | NCR1, NK cell-activating receptor, Lymphocyte antigen 94 homolog, Natural killer cell p46-related protein, Natural... |
| Origin: | human |
| MW: | 27.5 kD |
From 524.00€
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NPC2, His, Human
Item number: GSC-Z05706-100
The Niemann Pick type C (NPC) proteins, NPC1 and NPC2, are involved in the lysosomal storage disease, NPC disease. The formation of a NPC1-NPC2 protein-protein complex is believed to be necessary for the transfer of cholesterol and lipids out of the late endosomal (LE)/lysosomal (Lys) compartments. Mutations in...
| Keywords: | NPC2, Epididymal secretory protein E1, Human epididymis-specific protein 1, Niemann-Pick disease type C2 protein, NPC... |
| Origin: | human |
| MW: | 15.67 kD |
From 336.00€
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NPR1/NPRA mFc Chimera, Human
Item number: GSC-Z05707-100
NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation,...
| Keywords: | NPR1, Guanylate cyclase A, Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A |
| Origin: | human |
| MW: | 74.56 kD |
From 578.00€
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NRAS, His, Human
Item number: GSC-Z05709-100
NRas is a key mediator of the mitogenic pathway in normal cells and in cancer cells. Its dynamics and nanoscale organization at the plasma membrane (PM) facilitate its signaling. NRas activity is mediated and regulated by its dynamic interactions with functional (Grb2, BRAF, NF1, and GPI-nucleated) clusters at the PM.
| Keywords: | NRAS, GTPase NRas, Transforming protein N-Ras |
| Origin: | human |
| MW: | 22.29 kD |
From 497.00€
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OGN/Osteoglycin, His, Human
Item number: GSC-Z05713-100
Osteoglycin (OGN, a.k.a. mimecan) belongs to cluster III of the small leucine-rich proteoglycans (SLRP) of the extracellular matrix (ECM). In vertebrates OGN is a characteristic ECM protein of bone. The function of OGN has mainly been studied in mammals in which it regulates collagen fibrillogenesis, the efficiency...
| Keywords: | OGN, Mimecan, Osteoglycin, Osteoinductive factor |
| Origin: | human |
| MW: | 32.83 kD |
From 524.00€
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Oncostatin M/OSM, His, Human
Item number: GSC-Z05714-100
OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses...
| Keywords: | OSM, Oncostatin-M |
| Origin: | human |
| MW: | 23.24 kD |
From 376.00€
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Osteoactivin/GPNMB, His, Human
Item number: GSC-Z05723-100
GPNMB is highly expressed in macrophages and microglia, which are cells involved with innate immune response in the periphery and the brain, respectively. Some studies have shown increased levels of GPNMB in pro-inflammatory conditions, such as LPS treatment, and in pathological conditions, such as neurodegenerative...
| Keywords: | GPNMB, Transmembrane glycoprotein NMB, Hematopoietic growth factor inducible neurokinin-1 type |
| Origin: | human |
| MW: | 53.1 kD |
From 497.00€
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OX40/TNFRSF4/CD134 hFc Chimera, Human
Item number: GSC-Z05727-100
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation, its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following...
| Keywords: | TNFRSF4, ACT35 antigen, OX40L receptor, Tumor necrosis factor receptor superfamily member 4, TAX... |
| Origin: | human |
| MW: | 46.8 kD |
From 376.00€
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