Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human RNF43 Protein, hFc Tag
Item number: DIM-PME100761.10
Recombinant human RNF43 protein with C-terminal human Fc tag. RNF43(Glu43-Tyr197) hFc(Glu99-Ala330), Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components...
| Keywords: | RNF124, SSPCS, URCC |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 39.4 kD |
From 151.00€
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Human RNF43 Protein, mFc Tag
Item number: DIM-PME100762.10
Recombinant human RNF43 protein with C-terminal mouse Fc tag. RNF43(Glu43-Tyr197) mFc(Pro99-Lys330), Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components...
| Keywords: | RNF124, SSPCS, URCC |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 39.4 kD |
From 151.00€
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Human CLDN5 Protein, hFc Tag
Item number: DIM-PME100763.10
Recombinant human CLDN5 protein with C-terminal human Fc tag. CLDN5(Met29-Arg81) hFc(Glu99-Ala330), Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space. [The UniProt Consortium]
| Keywords: | Claudin-5, TMDVCF, AWAL, TMVCF |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 32.1 kD |
From 176.00€
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Human ITGAX and ITGB2 Heterodimer Protein, His Tag and...
Item number: DIM-PME100764.10
Heterodimer protein contains recombinant human ITGAX protein with C-terminal 6×His tag and human ITGB2 protein with C-terminal human Fc tag. ITGAX(Phe20-Pro1107) 6×His tag and ITGB2(Gln23-Asn700) hFc(Glu99-Ala330), Protein function: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence...
| Keywords: | Integrin alpha-XandIntegrin beta-2 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 120.6/ kD |
From 183.00€
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Human TIMP4 Protein, hFc Tag
Item number: DIM-PME100765.10
Recombinant human TIMP4 protein with C-terminal human Fc tag. TIMP4(Cys30-Pro224) hFc(Glu99-Ala330), Protein function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. [The...
| Keywords: | TIMP-4 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 48.6 kD |
From 183.00€
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Human Trop2 Protein, His Tag
Item number: DIM-PME100766.10
Recombinant human Trop2 protein with C-terminal 6×His tag. TROP2(His27-Thr274) 6×His tag, Protein function: May function as a growth factor receptor. [The UniProt Consortium]
| Keywords: | TACSTD2, GA733-1, M1S1, TROP2 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 28.7 kD |
From 151.00€
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Human CD72 Protein, hFc Tag
Item number: DIM-PME100767.10
Recombinant human CD72 protein with N-terminal human Fc tag. hFc(Glu99-Ala330) CD72(Arg117-Asp359), Protein function: Plays a role in B-cell proliferation and differentiation. [The UniProt Consortium]
| Keywords: | Lyb-2 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 54.2 kD |
From 176.00€
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Human B7-H7 Protein, hFc Tag
Item number: DIM-PME100768.10
Recombinant human B7-H7 protein with C-terminal human Fc tag. B7-H7(Ile23-Asn344) hFc(Glu99-Ala330), Protein function: Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. [The...
| Keywords: | HHLA2 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 63.1 kD |
From 176.00€
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Human FGF21 Protein, hFc Tag
Item number: DIM-PME100769.10
Recombinant human FGF21 protein with C-terminal human Fc tag. FGF21(His29-Ser209) hFc(Glu99-Ala330), Protein function: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. [The...
| Keywords: | Fibroblast growth factor 21, FGF-21 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 45.5 kD |
From 151.00€
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Human TPSAB1 Protein, His Tag
Item number: DIM-PME100770.10
Recombinant human TPSAB1 Protein with C-terminal 6×His tag. TPSAB1(Ala19-Pro275) 6×His tag, Protein function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large...
| Keywords: | Tryptase-1, Tryptase I, Tryptase alpha-1 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 29.6 kD |
From 151.00€
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Human ADAMTS1 Protein, His Tag
Item number: DIM-PME100771.10
Recombinant human ADAMTS1 Protein with C-terminal 6×His tag. ADAMTS1(Leu50-Ser967) 6×His tag, Protein function: Cleaves aggrecan, a cartilage proteoglycan, at the '1938- Glu-, -Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity....
| Keywords: | ADAM-TS 1, ADAM-TS1, ADAMTS-1, METH-1 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 101.1 kD |
From 176.00€
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Human IFNAR1 Protein, hFc Tag
Item number: DIM-PME100773.10
Recombinant Human IFNAR1 Protein with C-terminal human Fc tag. IFNAR1(Lys28-Lys436) hFc(Glu99-Ala330), Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986)....
| Keywords: | AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 73.3 kD |
From 176.00€
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