Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CD74(milatuzumab biosimilar) mAb
Item number: DIM-BME100170.100
Protein function: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and...
| Keywords: | Anti-DHLAG, Anti-CD74(milatuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD79B(polatuzumab biosimilar) mAb
Item number: DIM-BME100171.100
Protein function: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by...
| Keywords: | Anti-B29, Anti-IGB, Anti-CD79B(polatuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD166(praluzatamab biosimilar) mAb
Item number: DIM-BME100172.100
Protein function: Cell adhesion molecule that mediates both heterotypic cell- cell contacts via its interaction with CD6, as well as homotypic cell- cell contacts (PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T-cell activation and proliferation via...
| Keywords: | Anti-ALCAM, Anti-MEMD, Anti-CD166(praluzatamab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-TIM3(sabatolimab biosimilar) mAb
Item number: DIM-BME100173.100
Protein function: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand (PubMed:24825777). Regulates...
| Keywords: | Anti-HAVCR2, Anti-TIMD3, Anti-TIM3(sabatolimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-AXL(mecbotamab biosimilar) mAb
Item number: DIM-BME100175.100
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface...
| Keywords: | Anti-UFO, Anti-AXL(mecbotamab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD93(biosimilar) mAb
Item number: DIM-BME100176.100
Protein function: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion....
| Keywords: | Anti-C1QR1, Anti-MXRA4, Anti-CD93(biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-FOLR1(mirvetuximab biosimilar) mAb
Item number: DIM-BME100178.100
Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation...
| Keywords: | Anti-FBP, Anti-FOLR, Anti-FRalpha, Anti-NCFTD, Anti-FOLR1(mirvetuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-TNFa(golimumab biosimilar) mAb
Item number: DIM-BME100179.100
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia,...
| Keywords: | Anti-DIF, Anti-TNF-alpha, Anti-TNFA, Anti-TNFSF2, Anti-cachexin, Anti-cachectin, Anti-TNFalpha, Anti-TNFa(golimumab... |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-GUCY2C (ICTCAR-CRC) mAb
Item number: DIM-BME100180.100
Protein function: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin. [The UniProt Consortium]
| Keywords: | Anti-DIAR6, Anti-GC-C, Anti-GUC2C, Anti-MECIL, Anti-MUCIL, Anti-STAR, Anti-GUCY2C (ICTCAR-CRC) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H3 (TAA06 biosimilar) mAb
Item number: DIM-BME100181.100
Protein function: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant...
| Keywords: | Anti-B7H3, Anti-CD276, Anti-B7 homolog 3, Anti-B7-H3 (TAA06 biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-TNFa(Certolizumab biosimilar) mAb
Item number: DIM-BME100183.100
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia,...
| Keywords: | Anti-DIF, Anti-TNF-alpha, Anti-TNFA, Anti-TNFSF2, Anti-cachexin, Anti-cachectin, Anti-TNFalpha, Anti-TNFa(Certolizumab... |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-EPCAM(oportuzumab biosimilar) mAb
Item number: DIM-BME100184.100
Protein function: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells...
| Keywords: | Anti-GA733-2, Anti-M1S2, Anti-M4S1, Anti-MIC18, Anti-TACSTD1, Anti-TROP1, Anti-EPCAM(oportuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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