Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-IFNG(emapalumab biosimilar) mAb
Item number: DIM-BME100141.100
Protein function: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and...
| Keywords: | Anti-IFN-gamma, Anti-Immune interferon, Anti-IFNG(emapalumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-GCGR(volagidemab biosimilar) mAb
Item number: DIM-BME100142.100
Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting....
| Keywords: | Anti-Glucagon receptor, Anti-GL-R, Anti-GCGR(volagidemab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-MASP2(narsoplimab biosimilar) mAb
Item number: DIM-BME100143.100
Protein function: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. [The UniProt Consortium]
| Keywords: | Anti-MASP-2, Anti-MASP2(narsoplimab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-LILRB2 (MK-4830) mAb
Item number: DIM-BME100145.100
Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042). Involved in the down-regulation of the immune response and the development of tolerance. Recognizes...
| Keywords: | Anti-LIR-2, Anti-ILT-4, Anti-MIR-10, Anti-CD85d, Anti-LILRB2 (MK-4830) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-ITGAV(abituzumab biosimilar) mAb
Item number: DIM-BME100146.100
Protein function: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase- 2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine...
| Keywords: | Anti-Integrin alpha-V, Anti-CD51, Anti-ITGAV(abituzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GPC3(Hu9F2) mAb
Item number: DIM-BME100147.100
Protein function: Cell surface proteoglycan that bears heparan sulfate (PubMed:14610063). Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH...
| Keywords: | Anti-Glypican-3, Anti-GTR2-2, Anti-MXR7, Anti-Intestinal protein OCI-5, Anti-GPC3(Hu9F2) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-HTRA1(galegenimab biosimilar) mAb
Item number: DIM-BME100149.100
Protein function: Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through...
| Keywords: | Anti-L56, Anti-Serine protease 11, Anti-HTRA1(galegenimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GP6(glenzocimab biosimilar) mAb
Item number: DIM-BME100150.100
Protein function: Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the...
| Keywords: | Anti-Glycoprotein 6, Anti-GPVI, Anti-GP6(glenzocimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-ENPP3(Xencor) mAb
Item number: DIM-BME100151.100
Protein function: Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (PubMed:29717535). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and...
| Keywords: | Anti-CD203c, Anti-NPP3, Anti-PD-Ibeta, Anti-ENPP3(Xencor) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-PDL1 (durvalumab biosimilar) mAb
Item number: DIM-BME100153.100
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443,...
| Keywords: | Anti-PD-L1, Anti-CD274, Anti-B7-H1, Anti-PDCD1L1, Anti-PDCD1LG1, Anti-PDL1 (durvalumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CLEC4C (litifilimab biosimilar) mAb
Item number: DIM-BME100155.100
Protein function: Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed:11748283, PubMed:21880719, PubMed:25995448). Specifically recognizes non-sialylated galactose- terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man...
| Keywords: | Anti-BDCA-2, Anti-CD303, Anti-CLEC4C (litifilimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD45 (apamistamab biosimilar) mAb
Item number: DIM-BME100156.100
Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first...
| Keywords: | Anti-B220, Anti-CD45, Anti-CD45R, Anti-GP180, Anti-L-CA, Anti-LCA, Anti-LY5, Anti-T200, Anti-CD45 (apamistamab biosimilar)... |
| Host: | Mouse |
| Species reactivity: | human |
From 120.00€
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