Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-ADAM9 (biosimilar) mAb
Item number: DIM-BME100064.100
Protein function: Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins. [The UniProt Consortium]
| Keywords: | Anti-CORD9, Anti-MCMP, Anti-MDC9, Anti-Mltng, Anti-ADAM9 (biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GITR(ragifilimab biosimilar) mAb
Item number: DIM-BME100065.100
Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. [The UniProt Consortium]
| Keywords: | Anti-AITR, Anti-GITR, Anti-TNFRSF18, Anti-CD357, Anti-GITR(ragifilimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GUCY2C(indusatumab biosimilar) mAb
Item number: DIM-BME100067.100
Protein function: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin. [The UniProt Consortium]
| Keywords: | Anti-DIAR6, Anti-GC-C, Anti-GUC2C, Anti-MECIL, Anti-MUCIL, Anti-STAR, Anti-GUCY2C(indusatumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-DLL3(Rovalpituzumab biosimilar) mAb
Item number: DIM-BME100068.100
Protein function: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. [The UniProt Consortium]
| Keywords: | Anti-SCDO1, Anti-DLL3(Rovalpituzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-GPRC5D (Talquetamab biosimilar) mAb
Item number: DIM-BME100072.100
| Keywords: | Anti-GPRC5D, Anti-GPRC5D (Talquetamab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-ROR1 (zilovertamab biosimilar) mAb
Item number: DIM-BME100073.100
Protein function: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear,...
| Keywords: | Anti-ROR1, Anti-NTRKR1, Anti-ROR1 (zilovertamab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-ITGA4 (natalizumab biosimilar) mAb
Item number: DIM-BME100074.100
Protein function: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin...
| Keywords: | Anti-CD49D, Anti-IA4, Anti-ITGA4 (natalizumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CLDN18.2 (zolbetuximab biosimilar) mAb
Item number: DIM-BME100075.100
Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [The UniProt Consortium]
| Keywords: | Anti-GC-182, Anti-MAB-362, Anti-MAB362, Anti-laudiximab, Anti-CLDN18.2 (zolbetuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-CD47(lemzoparlimab biosimilar) mAb
Item number: DIM-BME100076.100
Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells...
| Keywords: | Anti-CD47, Anti-MER6, Anti-IAP, Anti-CD47(lemzoparlimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-SELP(crizanlizumab biosimilar) mAb
Item number: DIM-BME100077.100
Protein function: Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis. [The UniProt Consortium]
| Keywords: | Anti-P-Selectin, Anti-CD62P, Anti-SELP, Anti-GMP-140, Anti-SELP(crizanlizumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H4(alsevalimab biosimilar) mAb
Item number: DIM-BME100078.100
Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in the suppression of...
| Keywords: | Anti-B7-H4, Anti-B7h.5, Anti-B7H4, Anti-B7S1, Anti-B7X, Anti-PRO1291, Anti-VCTN1, Anti-B7-H4(alsevalimab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-TSHR (K1-70) mAb
Item number: DIM-BME100080.100
Protein function: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate...
| Keywords: | Anti-CHNG1, Anti-hTSHR-I, Anti-LGR3, Anti-TSHR (K1-70) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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