Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CD19 (inebilizumab biosimilar)mAb
Item number: DIM-BME100051.100
Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling pathways that lead...
| Keywords: | Anti-CD19, Anti-4, Anti-VID3, Anti-GC12802, Anti-CD19 (inebilizumab biosimilar)mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-IL-4RA (dupilumab biosimilar)mAb
Item number: DIM-BME100052.100
Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In...
| Keywords: | Anti-CD124, Anti-IL-4RA, Anti-IL4RA, Anti-IL-4RA (dupilumab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-OX40( ivuxolimab biosimilar)mAb
Item number: DIM-BME100053.100
Protein function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. [The UniProt Consortium]
| Keywords: | Anti-TNFRSF4, Anti-OX40, Anti-CD134, Anti-OX40L receptor, Anti-ACT35, Anti-TXGP1L, Anti-OX40( ivuxolimab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-CSF1R(cabiralizumab biosimilar) mAb
Item number: DIM-BME100055.100
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of...
| Keywords: | Anti-CSF1R, Anti-C-FMS, Anti-CD115, Anti-CSFR, Anti-FIM2, Anti-FMS, Anti-M-CSFR, Anti-CSF1R(cabiralizumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-TNFa(Adalimumab biosimilar) mAb
Item number: DIM-BME100056.100
Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia,...
| Keywords: | Anti-DIF, Anti-TNF-alpha, Anti-TNFA, Anti-TNFSF2, Anti-cachexin, Anti-cachectin, Anti-TNFalpha, Anti-TNFa(Adalimumab... |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-HER3 (patritumab biosimilar)mAb
Item number: DIM-BME100057.100
Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase...
| Keywords: | Anti-HER3, Anti-ERBB3, Anti-HER3 (patritumab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-TNFSF11 (denosumab biosimilar)mAb
Item number: DIM-BME100058.100
Protein function: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the...
| Keywords: | Anti-CD254, Anti-hRANKL2, Anti-ODF, Anti-OPGL, Anti-OPTB2, Anti-RANKL, Anti-sOdf, Anti-TNLG6B, Anti-TRANCE, Anti-TNFSF11... |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-MUC1(gatipotuzumab biosimilar) mAb
Item number: DIM-BME100059.100
Protein function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. [The UniProt Consortium]
| Keywords: | Anti-ADMCKD, Anti-ADMCKD1, Anti-CA 15-3, Anti-CD227, Anti-EMA, Anti-H23AG, Anti-KL-6, Anti-MAM6, Anti-MCD, Anti-MCKD,... |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-VEGFR2 (ramucirumab biosimilar)mAb
Item number: DIM-BME100060.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of...
| Keywords: | Anti-CD309, Anti-FLK1, Anti-VEGFR, Anti-VEGFR2, Anti-VEGFR2 (ramucirumab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-VEGFA(bevacizumab biosimiar) mAb
Item number: DIM-BME100061.100
Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin....
| Keywords: | Anti-rhuMAb-VEGF, Anti-VEGFA(bevacizumab biosimiar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-LAG3 (relatlimab biosimilar)mAb
Item number: DIM-BME100062.100
Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell inhibitory...
| Keywords: | Anti-BMS-986016, Anti-ONO-4482, Anti-LAG3 (relatlimab biosimilar)mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-CCR8(10A11) mAb
Item number: DIM-BME100063.100
Protein function: Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. [The UniProt Consortium]
| Keywords: | Anti-CC-CKR-8, Anti-CCR-8, Anti-CDw198, Anti-CKRL1, Anti-CMKBR8, Anti-CMKBRL2, Anti-CY6, Anti-GPRCY6, Anti-TER1,... |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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