Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-TIGIT (etigilimab biosimilar) mAb
Item number: DIM-BME100024.100
Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | Anti-TIGIT, Anti-SIG9, Anti-STM3, Anti-TIGIT (etigilimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD20 (rituximab biosimilar) mAb
Item number: DIM-BME100025.100
Protein function: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component...
| Keywords: | Anti-B1, Anti-Bp35, Anti-CD20, Anti-CVID5, Anti-LEU-16, Anti-MS4A2, Anti-S7, Anti-CD20 (rituximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-TIGIT (tiragolumab biosimilar) mAb
Item number: DIM-BME100026.100
Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | Anti-TIGIT, Anti-SIG9, Anti-STM3, Anti-TIGIT (tiragolumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-TIGIT (vibostolimab biosimilar) mAb
Item number: DIM-BME100027.100
Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | Anti-TIGIT, Anti-SIG9, Anti-STM3, Anti-TIGIT (vibostolimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-BCMA (belantamab biosimilar) mAb
Item number: DIM-BME100028.100
Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt Consortium]
| Keywords: | Anti-CD269, Anti-TNFRSF17, Anti-BCM, Anti-BCMA, Anti-BCMA (belantamab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD22 (pinatuzumab biosimilar) mAb
Item number: DIM-BME100029.100
Protein function: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids...
| Keywords: | Anti-CD22, Anti-SIGLEC2, Anti-BL-CAM, Anti-SIGLEC-2, Anti-Siglec2, Anti-SIGLEC2FLJ22814, Anti-CD22 (pinatuzumab... |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-TweakR (enavatuzumab biosimilar) mAb
Item number: DIM-BME100031.100
Protein function: Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. [The UniProt Consortium]
| Keywords: | Anti-TNFRSF12A, Anti-FGF-inducible 14, Anti-FN14, Anti-TweakR, Anti-CD266, Anti-TweakR (enavatuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-TNFRSF10B (tigatuzumab biosimilar) mAb
Item number: DIM-BME100032.100
Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases...
| Keywords: | Anti-TNFRSF10B, Anti-TRAILR2, Anti-TRAIL-R2, Anti-CD262, Anti-DR5, Anti-KILLER, Anti-TRICK2, Anti-ZTNFR9, Anti-TRICKB,... |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-AXL (enapotamab biosimilar) mAb
Item number: DIM-BME100033.100
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface...
| Keywords: | Anti-AXL, Anti-UFO, Anti-AXL (enapotamab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-EGFR (Cetuximab biosimilar) mAb
Item number: DIM-BME100034.100
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Keywords: | Anti-EGFR, Anti-ERBB, Anti-ERBB1, Anti-HER1, Anti-PIG61, Anti-mENA, Anti-EGFR (Cetuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-CEACAM5 (labetuzumab biosimilar) mAb
Item number: DIM-BME100035.100
Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6...
| Keywords: | Anti-CEACAM-5, Anti-CD66e, Anti-CEA, Anti-Meconium antigen 100, Anti-CEACAM5 (labetuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-ICAM-1 (bersanlimab biosimilar) mAb
Item number: DIM-BME100036.100
Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. [The UniProt Consortium]
| Keywords: | Anti-ICAM1, Anti-BB2, Anti-CD54, Anti-P3.58, Anti-ICAM-1 (bersanlimab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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