Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-B7-H3 (enoblituzumab biosimilar) mAb
Item number: DIM-BME100010.100
Protein function: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant...
| Keywords: | Anti-B7-H3, Anti-CD276, Anti-B7 homolog 3, Anti-B7-H3 (enoblituzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-SARS-CoV-2 (CB6 biosimilar) mAb
Item number: DIM-BME100011.100
Protein function: [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2 (PubMed:32142651, PubMed:33607086, PubMed:32155444). When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell...
| Keywords: | Anti-S protein RBD, Anti-Spike glycoprotein Receptor-binding domain, Anti-S glycoprotein RBD, Anti-Spike protein RBD,... |
| Host: | Human |
| Species reactivity: | SARS-CoV-2 |
From 120.00€
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Anti-ICOS (vopratelimab biosimilar) mAb
Item number: DIM-BME100012.100
Protein function: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for...
| Keywords: | Anti-ICOS, Anti-CD278, Anti-AILIM, Anti-Inducible T-cell costimulator, Anti-ICOS (vopratelimab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD33 (gemtuzumab biosimilar) mAb
Item number: DIM-BME100015.100
Protein function: Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state (PubMed:10611343, PubMed:15597323, PubMed:11320212). Preferentially recognizes and binds alpha-2,3- and more avidly alpha-2,6-linked...
| Keywords: | Anti-CD33, Anti-SIGLEC3, Anti-gp67, Anti-CD33 (gemtuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-BCMA (biosimilar) mAb
Item number: DIM-BME100016.100
Protein function: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [The UniProt Consortium]
| Keywords: | Anti-CD269, Anti-TNFRSF17, Anti-BCM, Anti-BCMA, Anti-BCMA (biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD30 (brentuximab biosimilar) mAb
Item number: DIM-BME100017.100
Protein function: Receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa- B (PubMed:8999898). [The UniProt Consortium]
| Keywords: | Anti-TNFRSF8, Anti-CD30, Anti-D1S166E, Anti-Ki-1, Anti-CD30 (brentuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-CD27 (varlilumab biosimilar) mAb
Item number: DIM-BME100018.100
Protein function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. [The UniProt Consortium]
| Keywords: | Anti-CD27, Anti-TNFRSF7, Anti-S152, Anti-T14, Anti-Tp55, Anti-CD27 (varlilumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-EPHA3 (ifabotuzumab biosimilar) mAb
Item number: DIM-BME100019.100
Protein function: Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling...
| Keywords: | Anti-TYRO4, Anti-HEK4, Anti-ETK1, Anti-ETK, Anti-EK4, Anti-HEK, Anti-EPHA3 (ifabotuzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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Anti-CD40 (iscalimab biosimilar) mAb
Item number: DIM-BME100020.100
Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | Anti-CD40, Anti-Bp50, Anti-CDW40, Anti-MGC9013, Anti-TNFRSF5, Anti-p50, Anti-CD40 (iscalimab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-Mesothelin (amatuximab biosimilar) mAb
Item number: DIM-BME100021.100
Protein function: Membrane-anchored forms may play a role in cellular adhesion. [The UniProt Consortium]
| Keywords: | Anti-MSLN, Anti-Mesothelin, Anti-MPF, Anti-Mesothelin (amatuximab biosimilar) mAb |
| Host: | Chimeric |
| Species reactivity: | human |
From 120.00€
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Anti-CTLA-4 (ipilimumab biosimilar) mAb
Item number: DIM-BME100022.100
Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | Anti-CTLA4, Anti-CD152, Anti-CTLA-4 (ipilimumab biosimilar) mAb |
| Host: | Human |
| Species reactivity: | human |
From 120.00€
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Anti-Trop2 (sacituzumab biosimilar) mAb
Item number: DIM-BME100023.100
Protein function: May function as a growth factor receptor. [The UniProt Consortium]
| Keywords: | Anti-TACSTD2, Anti-GA733-1, Anti-M1S1, Anti-TROP2, Anti-Trop2 (sacituzumab biosimilar) mAb |
| Host: | Humanized |
| Species reactivity: | human |
From 120.00€
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