Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-EGFRVIII antibody(2E12), IgG1 Chimeric mAb
Item number: DIM-DMC101040.10
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Keywords: | Anti-EGFR, Anti-RBB, Anti-RBB1, Anti-ER1, Anti-IG61, Anti-ENA, Anti-EGFRVIII antibody(2E12), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-CDH3 antibody(6A10), IgG1 Chimeric mAb
Item number: DIM-DMC101041.10
Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. [The UniProt Consortium]
| Keywords: | Anti-CDHP, Anti-HJMD, Anti-PCAD, Anti-CDH3 antibody(6A10), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-pTHEMIS antibody(4F2), IgG1 Chimeric mAb
Item number: DIM-DMC101054.10
Protein function: Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling...
| Keywords: | Anti-THEMIS, Anti-C6orf190, Anti-C6orf207, Anti-pTHEMIS antibody(4F2), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-CD3E antibody(1G2), IgG1 Chimeric mAb
Item number: DIM-DMC101085.10
Protein function: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z....
| Keywords: | Anti-CD3e, Anti-T3E, Anti-CD3E antibody(1G2), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-DLL3 antibody(67E6), IgG1 Chimeric mAb
Item number: DIM-DMC101089.10
Protein function: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. [The UniProt Consortium]
| Keywords: | Anti-SCDO1, Anti-DLL3 antibody(67E6), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-PVRIG antibody(6G7), IgG1 Chimeric mAb
Item number: DIM-DMC101091.10
Protein function: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. [The UniProt Consortium]
| Keywords: | Anti-C7orf15, Anti-CD112R, Anti-PVRIG antibody(6G7), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-PGLYRP1 antibody(1E10), IgG1 Chimeric mAb
Item number: DIM-DMC101092.10
Protein function: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity...
| Keywords: | Anti-PGRP-S, Anti-PGLYRP1 antibody(1E10), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-CD147 antibody(2D2), IgG1 Chimeric mAb
Item number: DIM-DMC101093.10
Protein function: [Isoform 1]: Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes...
| Keywords: | Anti-Basigin, Anti-BSG, Anti-5F7, Anti-CD147, Anti-EMMPRIN, Anti-M6, Anti-OK, Anti-TCSF, Anti-CD147 antibody(2D2), IgG1... |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-B7H7 antibody(2D5), IgG1 Chimeric mAb
Item number: DIM-DMC101094.10
Protein function: Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. [The UniProt Consortium]
| Keywords: | Anti-HHLA2, Anti-B7H7 antibody(2D5), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-TFRC antibody(7C1), IgG1 Chimeric mAb
Item number: DIM-DMC101095.10
Protein function: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738). Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH...
| Keywords: | Anti-TR, Anti-TfR, Anti-TfR1, Anti-Trfr, Anti-T9, Anti-p90, Anti-CD71, Anti-TFRC antibody(7C1), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-SEZ6 antibody(31A10), IgG1 Chimeric mAb
Item number: DIM-DMC101096.10
Protein function: May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory...
| Keywords: | Anti-BSRPC, Anti-SEZ6 antibody(31A10), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-FLT3 antibody(19A5), IgG1 Chimeric mAb
Item number: DIM-DMC101110.10
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes...
| Keywords: | Anti-Flt-3, Anti-Flk-2, Anti-STK-1, Anti-CD135, Anti-FLK2, Anti-FLT-3, Anti-FLT3 antibody(19A5), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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