Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-BTLA (tifcemalimab biosimilar) mAb
Item number: DIM-BME100695.100
Research use only. Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14...
| Keywords: | Icatolimab,JS-004,JS004,JS 004,JS-4,JS4,JS 4,TAB-004,TAB004,TAB 004,TAB-4,TAB4,TAB 4, Anti-CD272, Anti-B- and T-lymphocyte... |
| Species reactivity: | human |
From 120.00€
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Anti-MAPT (tilavonemab biosimilar) mAb, biotinylated
Item number: DIM-BME100696B.100
Research use only. Protein function: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein...
| Keywords: | ABBV-8E12,ABBV8E12,ABBV 8E12, Anti-MAPTL, Anti-PHF-tau, Anti-Paired helical filament-tau, Anti-Neurofibrillary tangle... |
| Species reactivity: | human |
From 145.00€
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Anti-TNFRSF10B (tilogotamab biosimilar) mAb, biotinylated
Item number: DIM-BME100698B.100
Research use only. Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of...
| Keywords: | GEN-1029,GEN1029,GEN 1029, Anti-DR5, Anti-CD262, Anti-TRAIL-R2, Anti-TNFRSF10B, Anti-TRAIL receptor 2, Anti-Death receptor... |
| Species reactivity: | human |
From 145.00€
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Anti-AXL (tilvestamab biosimilar) mAb
Item number: DIM-BME100699.100
Research use only. Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at...
| Keywords: | BGB 149,BGB-149,BGB149, Anti-UFO, Anti-AXL, EC=2.7.10.1, Anti-AXL oncogene, Anti-Tyrosine-protein kinase receptor UFO |
| Species reactivity: | human |
From 120.00€
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Anti-AXL (tilvestamab biosimilar) mAb, biotinylated
Item number: DIM-BME100699B.100
Research use only. Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at...
| Keywords: | BGB 149,BGB-149,BGB149, Anti-UFO, Anti-AXL, EC=2.7.10.1, Anti-AXL oncogene, Anti-Tyrosine-protein kinase receptor UFO |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (tislelizumab biosimilar) mAb
Item number: DIM-BME100700.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | BGB-A317,BGB A317,TEVIMBRA,Tilelizumab,VDT-482,VDT 482,VDT482, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed... |
| Species reactivity: | human |
From 120.00€
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Anti-Trop2 (tizetatug biosimilar) mAb
Item number: DIM-BME100701.100
Research use only. Protein function: May function as a growth factor receptor. [The UniProt Consortium]
| Keywords: | TBC, Anti-GA733-1, Anti-TACSTD2, Anti-Cell surface glycoprotein Trop-2, Anti-Pancreatic carcinoma marker protein GA733-1,... |
| Species reactivity: | human |
From 120.00€
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Anti-EGFR (tomuzotuximab biosimilar) mAb
Item number: DIM-BME100702.100
Research use only. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN,...
| Keywords: | GT-MAB 5.2-GEX, Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Species reactivity: | human |
From 120.00€
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Anti-IL33 (torudokimab biosimilar) mAb
Item number: DIM-BME100704.100
Research use only. Protein function: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also...
| Keywords: | LY-3375880,LY3375880,LY 3375880,ZB-880,ZB880,ZB 880, Anti-C9orf26 |
| Species reactivity: | human |
From 120.00€
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Anti-IL33 (torudokimab biosimilar) mAb, biotinylated
Item number: DIM-BME100704B.100
Research use only. Protein function: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also...
| Keywords: | LY-3375880,LY3375880,LY 3375880,ZB-880,ZB880,ZB 880, Anti-C9orf26 |
| Species reactivity: | human |
From 145.00€
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Anti-IL33 (tozorakimab biosimilar) mAb, biotinylated
Item number: DIM-BME100705B.100
Research use only. Protein function: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also...
| Keywords: | MEDI-3506,MEDI3506,MEDI 3506, Anti-C9orf26 |
| Species reactivity: | human |
From 145.00€
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Anti-CTLA-4 (tremelimumab biosimilar) mAb, biotinylated
Item number: DIM-BME100707B.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | CP-675,CP675,CP 675,CP-675206,CP 675206,CP675206,IMJUDO,Ticilimumab, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic... |
| Species reactivity: | human |
From 145.00€
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