Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-IL6 (sirukumab biosimilar) mAb, biotinylated
Item number: DIM-BME100669B.100
Research use only. Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the...
| Keywords: | CNTO-136,CNTO136,CNTO 136,PLIVENSIA,Shirukumabu, Anti-CDF, Anti-IL-6, Anti-BSF-2, Anti-IFNB2, Anti-IFN-beta-2,... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-L1 (socazolimab biosimilar) mAb
Item number: DIM-BME100670.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | STI-1014,STI1014,STI 1014,STI-A1014,STI A1014,ZKAB-001,ZKAB001,ZKAB 001,ZKAB-1,ZKAB1,ZKAB 1, Anti-B7H1, Anti-PD-L1,... |
| Species reactivity: | human |
From 120.00€
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Anti-APP (solanezumab biosimilar) mAb
Item number: DIM-BME100671.100
Research use only. Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis (PubMed:25122912). Involved in cell...
| Keywords: | LY-2062430,LY 2062430,LY206430, Anti-A4 |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H5 (solnerstotug biosimilar) mAb, biotinylated
Item number: DIM-BME100672B.100
Research use only. Protein function: Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14- mediated MMP2 activation (PubMed:20666777). [The UniProt Consortium]
| Keywords: | SNS-101,SNS 101,SNS101, Anti-PP2135, Anti-Sisp-1, Anti-C10orf54, Anti-Platelet receptor Gi24, Anti-V-set immunoregulatory... |
| Species reactivity: | human |
From 145.00€
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Anti-CD40 (sotigalimab biosimilar) mAb
Item number: DIM-BME100674.100
Research use only. Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | APX 005,APX005,APX 005,APX5,APX-5,APX 5,EPI-0050,EPI0050,EPI 0050,EPI 50,EPI-50,EPI50, Anti-Bp50, Anti-CD40, Anti-CDw40,... |
| Species reactivity: | human |
From 120.00€
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Anti-TIM3 (surzebiclimab biosimilar) mAb, biotinylated
Item number: DIM-BME100681B.100
Research use only. Protein function: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand...
| Keywords: | BGB-A425,BGB A425, Anti-TIM3, Anti-TIM-3, Anti-CD366, Anti-TIMD-3, Anti-HAVCR2, Anti-HAVcr-2, Anti-T-cell membrane protein... |
| Species reactivity: | human |
From 145.00€
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Anti-VEGFA (suvemcitug biosimilar) mAb
Item number: DIM-BME100682.100
Research use only. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate...
| Keywords: | APX003,APX-003,BD0801,BD-0801,TK001,TK-001,Sevacizumab (not WHO assigned INN), Anti-VPF, Anti-VEGF, Anti-VEGFA,... |
| Species reactivity: | human |
From 120.00€
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Anti-CD19 (tafasitamab biosimilar) mAb, biotinylated
Item number: DIM-BME100683B.100
Research use only. Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling...
| Keywords: | ICP-B04,ICP B04,MOR 208,MOR208,MOR-208,XENP-5574,XENP5574,XENP 5574,XmAb-5574,XmAb5574,XmAb 5574, Anti-CD19,... |
| Species reactivity: | human |
From 145.00€
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Anti-NGF (tanezumab biosimilar) mAb
Item number: DIM-BME100687.100
Research use only. Protein function: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems (PubMed:14976160, PubMed:20978020). Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation,...
| Keywords: | PF-04383119,PF04383119,PF-4383119,PF4383119,RI-624,RI624,RI 624,RN-624,RN624,RN 624, Anti-NGF, Anti-NGFB, Anti-Beta-NGF,... |
| Species reactivity: | human |
From 120.00€
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Anti-CLDN18 (tecotabart biosimilar) mAb, biotinylated
Item number: DIM-BME100690B.100
Research use only. Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [The UniProt Consortium]
| Keywords: | LM-102,LM 102,LM102, Anti-CLDN18, Anti-Claudin-18 |
| Species reactivity: | human |
From 145.00€
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Anti-CD40 Ligand (tegoprubart biosimilar) mAb, biotinylated
Item number: DIM-BME100691B.100
Research use only. Protein function: Cytokine that acts as a ligand to CD40/TNFRSF5 (PubMed:1280226, PubMed:31331973). Costimulates T-cell proliferation and cytokine production (PubMed:8617933). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction...
| Keywords: | AT-1501,AT1501,AT 1501, Anti-CD40L, Anti-CD40LG |
| Species reactivity: | human |
From 145.00€
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Anti-IL4RA (telikibart biosimilar) mAb
Item number: DIM-BME100693.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | TBC, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 120.00€
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