Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-TIGIT (ociperlimab biosimilar) mAb
Item number: DIM-BME100596.100
Research use only. Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | BGB-A1217,BGB A1217,WCD-118,WCD118,WCD 118, Anti-TIGIT, Anti-VSIG9, Anti-T-cell immunoreceptor with Ig and ITIM domains,... |
| Species reactivity: | human |
From 120.00€
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Anti-CD20 (ofatumumab biosimilar) mAb, biotinylated
Item number: DIM-BME100597B.100
Research use only. Protein function: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC)...
| Keywords: | Arzerra,GSK-1841157,GSK1841157,,GSK 1841157,Kesimpta,OMB-157,OMB157,OMB 157, Anti-CD20, Anti-Bp35, Anti-MS4A1,... |
| Species reactivity: | human |
From 145.00€
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Anti-VEGFR2 (olinvacimab biosimilar) mAb, biotinylated
Item number: DIM-BME100599B.100
Research use only. Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and...
| Keywords: | SSS-23,SSS23,SSS 23,TTAC-0001,TTAC0001,TTAC 0001,TTAC-1,TTAC1,TTAC 1, Anti-KDR, Anti-FLK1, Anti-FLK-1, Anti-CD309,... |
| Species reactivity: | human |
From 145.00€
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Anti-LGALS3 (oloctinebart biosimilar) mAb
Item number: DIM-BME100600.100
Research use only. Protein function: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus:...
| Keywords: | TBC, Anti-L-31, Anti-MAC2, Anti-GALBP, Anti-Gal-3, Anti-CBP 35, Anti-Galectin-3, Anti-Lectin L-29, Anti-Mac-2 antigen,... |
| Species reactivity: | human |
From 120.00€
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Anti-IL6 (olokizumab biosimilar) mAb
Item number: DIM-BME100601.100
Research use only. Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the...
| Keywords: | Artlegia,CDP-6038,CDP6038,CDP 6038, Anti-CDF, Anti-IL-6, Anti-BSF-2, Anti-IFNB2, Anti-IFN-beta-2, Anti-Interleukin-6,... |
| Species reactivity: | human |
From 120.00€
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Anti-C5 (omoprubart biosimilar) mAb
Item number: DIM-BME100603.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | CAN106,CAN-106, Anti-C5, Anti-CPAMD4 |
| Species reactivity: | human |
From 120.00€
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Anti-PCSK9 (ongericimab biosimilar) mAb
Item number: DIM-BME100604.100
Research use only. Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2...
| Keywords: | JS-002,JS002,JS 002,JS-2,JS2,JS 2, Anti-PC9, Anti-NARC1, Anti-PCSK9, Anti-NARC-1, Anti-PSEC0052, EC=3.4.21.-,... |
| Species reactivity: | human |
From 120.00€
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Anti-CLDN18 (osemitamab biosimilar) mAb
Item number: DIM-BME100605.100
Research use only. Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [The UniProt Consortium]
| Keywords: | TST-001,TST001,TST 001,TST-1,TST1,TST 1, Anti-CLDN18, Anti-Claudin-18 |
| Species reactivity: | human |
From 120.00€
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Anti-CD3E (otelixizumab biosimilar) mAb, biotinylated
Item number: DIM-BME100606B.100
Research use only. Protein function: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D,...
| Keywords: | ChAglyCD3,GSK-2136525,GSK2136525,GSK 2136525,TRX4,TRX-4,TRX 4, Anti-T3E, Anti-CD3E, Anti-CD3e, Anti-T-cell surface... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-L1 (pacmilimab biosimilar) mAb, biotinylated
Item number: DIM-BME100609B.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | CX-072,CX072,CX 072, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1,... |
| Species reactivity: | human |
From 145.00€
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Anti-SEMA4D (pepinemab biosimilar) mAb
Item number: DIM-BME100614.100
Research use only. Protein function: Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed:20877282). Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of...
| Keywords: | VX15/2503,VX 15,VX-15,VX 15,VX 15/2503,VX-15/2503, Anti-A8, Anti-GR3, Anti-BB18, Anti-CD100, Anti-SEMA4D, Anti-C9orf164,... |
| Species reactivity: | human |
From 120.00€
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Anti-Her2 (pertuzumab biosimilar) mAb, biotinylated
Item number: DIM-BME100616B.100
Research use only. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for...
| Keywords: | R-1273,R1273,R 1273,RG-1273,RG 1273,RG1273,RO-4368451,RO4368451,RO 4368451, Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN... |
| Species reactivity: | human |
From 145.00€
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