Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-PD-1 (dostarlimab biosimilar) mAb, biotinylated
Item number: DIM-BME100480B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | ANB 011,ANB011,ANB-011,GSK-4057190,GSK4057190,JEMPERLI,TSR 042,TSR042,TSR-042,WBP 285,WBP285,WBP-285, Anti-CD279,... |
| Species reactivity: | human |
From 145.00€
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Anti-IL4RA (drotokibart biosimilar) mAb
Item number: DIM-BME100482.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | TBC, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 120.00€
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Anti-IL4RA (drotokibart biosimilar) mAb, biotinylated
Item number: DIM-BME100482B.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | TBC, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 145.00€
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Anti-TMEM219 (ebrasodebart biosimilar) mAb
Item number: DIM-BME100484.100
Research use only. Protein function: Cell death receptor specific for IGFBP3, may mediate caspase- 8-dependent apoptosis upon ligand binding. [The UniProt Consortium]
| Keywords: | Ent-001,Ent001,Ent 001, Anti-TMEM219, Anti-IGFBP-3R, Anti-Transmembrane protein 219, Anti-Insulin-like growth... |
| Species reactivity: | human |
From 120.00€
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Anti-C5 (eculizumab biosimilar) mAb
Item number: DIM-BME100486.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | 5G1-1,5G1.1,Soliris, Anti-C5, Anti-CPAMD4 |
| Species reactivity: | human |
From 120.00€
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Anti-C5 (eculizumab biosimilar) mAb, biotinylated
Item number: DIM-BME100486B.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | 5G1-1,5G1.1,Soliris, Anti-C5, Anti-CPAMD4 |
| Species reactivity: | human |
From 145.00€
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Anti-CD117 (eglatoprutug biosimilar) mAb
Item number: DIM-BME100487.100
Research use only. Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in...
| Keywords: | TBC, Anti-PBT, Anti-KIT, Anti-SCFR, Anti-CD117, Anti-p145 c-kit, EC=2.7.10.1, Anti-Proto-oncogene c-Kit, Anti-Piebald... |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H4 (emiltatug biosimilar) mAb
Item number: DIM-BME100490.100
Research use only. Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in...
| Keywords: | XMT-1660,XMT1660,XMT 1660, Anti-B7-H4, Anti-B7h.5, Anti-B7 homolog 4, Anti-Protein B7S1, Anti-T-cell costimulatory... |
| Species reactivity: | human |
From 120.00€
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Anti-TNFRSF1B (emunkitug biosimilar) mAb, biotinylated
Item number: DIM-BME100493B.100
Research use only. Protein function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects...
| Keywords: | TBC, Anti-TNFBR, Anti-TNFRSF1B |
| Species reactivity: | human |
From 145.00€
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Anti-CD38 (erzotabart biosimilar) mAb, biotinylated
Item number: DIM-BME100497B.100
Research use only. Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. [The UniProt...
| Keywords: | GEN-3014,GEN3014,GEN 3014, Anti-T10, Anti-CD38, Anti-ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, Anti-cADPr hydrolase 1,... |
| Species reactivity: | human |
From 145.00€
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Anti-CTLA-4 (evalstotug biosimilar) mAb, biotinylated
Item number: DIM-BME100500B.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | BA3071,BA-3071, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic... |
| Species reactivity: | human |
From 145.00€
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Anti-4-1BB (exlinkibart biosimilar) mAb
Item number: DIM-BME100504.100
Research use only. Protein function: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. [The UniProt Consortium]
| Keywords: | LVGN-6051,LVGN6051, Anti-CD137, Anti-CDw137, Anti-TNFRSF9, Anti-T-cell antigen ILA, Anti-4-1BB ligand receptor,... |
| Species reactivity: | human |
From 120.00€
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