Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CTLA-4 (botensilimab biosimilar) mAb, biotinylated
Item number: DIM-BME100440B.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | AGEN-1181,AGEN1181, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic... |
| Species reactivity: | human |
From 145.00€
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Anti-LAG3 (brivestobart biosimilar) mAb
Item number: DIM-BME100441.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | BSI-045B,BSI045B,BSI 045B,TQC-2731,TQC2731,TQC 2731, Anti-FDC |
| Species reactivity: | human |
From 120.00€
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Anti-CD19 (budoprutug biosimilar) mAb
Item number: DIM-BME100443.100
Research use only. Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling...
| Keywords: | VB119,VB-119, Anti-CD19, Anti-B-lymphocyte antigen CD19, Anti-Differentiation antigen CD19, Anti-T-cell surface antigen... |
| Species reactivity: | human |
From 120.00€
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Anti-LAG3 (bulumtatug biosimilar) mAb
Item number: DIM-BME100444.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | TBC, Anti-FDC |
| Species reactivity: | human |
From 120.00€
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Anti-CCR8 (cafelkibart biosimilar) mAb, biotinylated
Item number: DIM-BME100445B.100
Research use only. Protein function: Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. [The UniProt Consortium]
| Keywords: | LM108,LM-108,LM 108, Anti-TER1, Anti-CCR8, Anti-CCR-8, Anti-CKRL1, Anti-CDw198, Anti-GPRCY6, Anti-CKR-L1, Anti-GPR-CY6,... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (cemiplimab biosimilar) mAb, biotinylated
Item number: DIM-BME100450B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | Libtayo,REGN-2810,REGN2810,SAR-439684,SAR439684, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death... |
| Species reactivity: | human |
From 145.00€
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Anti-SELPLG (cepeprubart biosimilar) mAb
Item number: DIM-BME100452.100
Research use only. Protein function: A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. [The UniProt...
| Keywords: | SelK-2,SelK2, Anti-CD162, Anti-SELPLG, Anti-PSGL-1, Anti-Selectin P ligand, Anti-P-selectin glycoprotein ligand 1 |
| Species reactivity: | human |
From 120.00€
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Anti-CLDN18 (ciletatug biosimilar) mAb
Item number: DIM-BME100455.100
Research use only. Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [The UniProt Consortium]
| Keywords: | TBC, Anti-CLDN18, Anti-Claudin-18 |
| Species reactivity: | human |
From 120.00€
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Anti-IL6 (clazakizumab biosimilar) mAb
Item number: DIM-BME100456.100
Research use only. Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the...
| Keywords: | ALD 518,ALD-518,ALD518,BMS-645429,BMS645429,BMS-945429,BMS945429,CSL-300,CSL300, Anti-CDF, Anti-IL-6, Anti-BSF-2,... |
| Species reactivity: | human |
From 120.00€
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Anti-IL6 (clazakizumab biosimilar) mAb, biotinylated
Item number: DIM-BME100456B.100
Research use only. Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the...
| Keywords: | ALD 518,ALD-518,ALD518,BMS-645429,BMS645429,BMS-945429,BMS945429,CSL-300,CSL300, Anti-CDF, Anti-IL-6, Anti-BSF-2,... |
| Species reactivity: | human |
From 145.00€
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Anti-IL4RA (comekibart biosimilar) mAb
Item number: DIM-BME100457.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | BC005,BC-005,BC 005,MG-010,MG010,MG 010,MG-K10,MG K10, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 120.00€
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Anti-IL4RA (comekibart biosimilar) mAb, biotinylated
Item number: DIM-BME100457B.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | BC005,BC-005,BC 005,MG-010,MG010,MG 010,MG-K10,MG K10, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 145.00€
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