Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-C5 (pozelimab biosimilar) mAb
Item number: DIM-BME100624.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | REGN 3918,REGN3918,REGN 3918, Anti-C5, Anti-CPAMD4 |
| Species reactivity: | human |
From 120.00€
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Anti-PD-1 (prolgolimab biosimilar) mAb, biotinylated
Item number: DIM-BME100628B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | BCD-100, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (pucotenlimab biosimilar) mAb, biotinylated
Item number: DIM-BME100629B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | HX-008,HX008,HX 008,HX-8,HX8,HX 8,Puyouheng, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 145.00€
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Anti-VEGFR2 (pulocimab biosimilar) mAb, biotinylated
Item number: DIM-BME100630B.100
Research use only. Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and...
| Keywords: | AK-109, AK109,AK 109, Anti-KDR, Anti-FLK1, Anti-FLK-1, Anti-CD309, Anti-VEGFR-2, Anti-Fetal liver kinase 1, Anti-Kinase... |
| Species reactivity: | human |
From 145.00€
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Anti-B7-H4 (puxitatug biosimilar) mAb, biotinylated
Item number: DIM-BME100631B.100
Research use only. Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in...
| Keywords: | AZD-8205, AZD 8205, AZD8205, Anti-B7-H4, Anti-B7h.5, Anti-B7 homolog 4, Anti-Protein B7S1, Anti-T-cell costimulatory... |
| Species reactivity: | human |
From 145.00€
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Anti-CTLA-4 (quavonlimab biosimilar) mAb, biotinylated
Item number: DIM-BME100632B.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | AK-107,MK-1308,AK107,MK1308,AK 107,MK 1308, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4,... |
| Species reactivity: | human |
From 145.00€
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Anti-LIGHT (quisovalimab biosimilar) mAb, biotinylated
Item number: DIM-BME100633B.100
Research use only. Protein function: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM (PubMed:9462508, PubMed:10754304). Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and...
| Keywords: | AEVI-002,AEVI002,AEVI 002,AEVI-2,AEVI2,AEVI 2,AVTX-002,AVTX002,AVTX 002,AVTX-2,AVTX2,AVTX 2,CERC 002,CERC-002,CERC002,CERC... |
| Species reactivity: | human |
From 145.00€
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Anti-IL1RL2 (recibokibart biosimilar) mAb
Item number: DIM-BME100639.100
Research use only. Protein function: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36- dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling...
| Keywords: | TBC, Anti-IL-36R, Anti-IL1RL2, Anti-IL1RRP2, Anti-IL-1Rrp2, Anti-IL1R-rp2, Anti-IL-36 receptor, Anti-Interleukin-1... |
| Species reactivity: | human |
From 120.00€
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Anti-VEGFB (reflocibart biosimilar) mAb
Item number: DIM-BME100640.100
Research use only. Protein function: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. [The UniProt Consortium]
| Keywords: | CSL-346,CSL346,CSL 346,2H10, Anti-VRF, Anti-VEGFB, Anti-VEGF-B, Anti-VEGF-related factor, Anti-Vascular endothelial growth... |
| Species reactivity: | human |
From 120.00€
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Anti-APP (remternetug biosimilar) mAb
Item number: DIM-BME100641.100
Research use only. Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis (PubMed:25122912). Involved in cell...
| Keywords: | LY-3372993,LY 3372993,LY3372993,N3pG 4,N3pG4,N3PG-IV, Anti-A4 |
| Species reactivity: | human |
From 120.00€
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Anti-PVRIG (remzistotug biosimilar) mAb, biotinylated
Item number: DIM-BME100642B.100
Research use only. Protein function: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. [The UniProt Consortium]
| Keywords: | TBC, Anti-PVRIG, Anti-CD112R, Anti-C7orf15, Anti-CD112 receptor, Anti-Transmembrane protein PVRIG, Anti-Poliovirus... |
| Species reactivity: | human |
From 145.00€
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Anti-IL5 (reslizumab biosimilar) mAb
Item number: DIM-BME100644.100
Research use only. Protein function: Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. [The UniProt Consortium]
| Keywords: | CDP-835,CDP835,CDP 835,CEP-38072,CEP38072,CEP 38072,CINQAERO,CINQAIR,Cinquil,CTx-55700,CTx55700,Ctx... |
| Species reactivity: | human |
From 120.00€
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