Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-PD-1 (pucotenlimab biosimilar) mAb, biotinylated
Item number: DIM-BME100629B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | HX-008,HX008,HX 008,HX-8,HX8,HX 8,Puyouheng, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 145.00€
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Anti-VEGFR2 (pulocimab biosimilar) mAb, biotinylated
Item number: DIM-BME100630B.100
Research use only. Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and...
| Keywords: | AK-109, AK109,AK 109, Anti-KDR, Anti-FLK1, Anti-FLK-1, Anti-CD309, Anti-VEGFR-2, Anti-Fetal liver kinase 1, Anti-Kinase... |
| Species reactivity: | human |
From 145.00€
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Anti-B7-H4 (puxitatug biosimilar) mAb, biotinylated
Item number: DIM-BME100631B.100
Research use only. Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in...
| Keywords: | AZD-8205, AZD 8205, AZD8205, Anti-B7-H4, Anti-B7h.5, Anti-B7 homolog 4, Anti-Protein B7S1, Anti-T-cell costimulatory... |
| Species reactivity: | human |
From 145.00€
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Anti-CTLA-4 (quavonlimab biosimilar) mAb, biotinylated
Item number: DIM-BME100632B.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | AK-107,MK-1308,AK107,MK1308,AK 107,MK 1308, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4,... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (spartalizumab biosimilar) mAb, biotinylated
Item number: DIM-BME100676B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | PDR 001,PDR-001,PDR001, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 145.00€
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Anti-IL4RA (stapokibart biosimilar) mAb, biotinylated
Item number: DIM-BME100677B.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | CM-310,CM 310,CM310, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 145.00€
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Anti-CD22 (suciraslimab biosimilar) mAb
Item number: DIM-BME100678.100
Research use only. Protein function: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid. The sialic acid recognition site can be masked by cis interactions...
| Keywords: | SM-03,SM03,SM 03,SM-3,SM3,SM 3,SM-06,SM06,SM 06,SM-6,SM6,SM 6, Anti-CD22, Anti-BL-CAM, Anti-SIGLEC2, Anti-Siglec-2,... |
| Species reactivity: | human |
From 120.00€
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Anti-PD-L1 (sudubrilimab biosimilar) mAb, biotinylated
Item number: DIM-BME100679B.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | HS636,HS-636,HS 636, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1,... |
| Species reactivity: | human |
From 145.00€
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Anti-VEGFA (suvemcitug biosimilar) mAb, biotinylated
Item number: DIM-BME100682B.100
Research use only. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate...
| Keywords: | APX003,APX-003,BD0801,BD-0801,TK001,TK-001,Sevacizumab (not WHO assigned INN), Anti-VPF, Anti-VEGF, Anti-VEGFA,... |
| Species reactivity: | human |
From 145.00€
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Anti-PCSK9 (tafolecimab biosimilar) mAb, biotinylated
Item number: DIM-BME100684B.100
Research use only. Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2...
| Keywords: | IBI 306,IBI-306,IBI306, Anti-PC9, Anti-NARC1, Anti-PCSK9, Anti-NARC-1, Anti-PSEC0052, EC=3.4.21.-, Anti-Proprotein... |
| Species reactivity: | human |
From 145.00€
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Anti-TIGIT (tamgiblimab biosimilar) mAb
Item number: DIM-BME100686.100
Research use only. Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | IBI-939,IBI939,IBI 939, Anti-TIGIT, Anti-VSIG9, Anti-T-cell immunoreceptor with Ig and ITIM domains, Anti-V-set and... |
| Species reactivity: | human |
From 120.00€
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Anti-TIGIT (tamgiblimab biosimilar) mAb, biotinylated
Item number: DIM-BME100686B.100
Research use only. Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | IBI-939,IBI939,IBI 939, Anti-TIGIT, Anti-VSIG9, Anti-T-cell immunoreceptor with Ig and ITIM domains, Anti-V-set and... |
| Species reactivity: | human |
From 145.00€
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