Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human IL2RA Protein, His Tag
Item number: DIM-PME100098.10
Recombinant human IL2RA Protein with C-terminal 6×His tag. IL2RA(Glu22-Cys213) 6×His tag, Protein function: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive...
| Keywords: | IL2RA, CD25, p55, IL2-RA, IL-2-RA |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 22.6 kD |
From 120.00€
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Human EGFR Protein, His Tag
Item number: DIM-PME100099.10
Recombinant human EGFR Protein with C-terminal 6×His tag. EGFR(Leu25-Ser645) 6×His tag, Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725,...
| Keywords: | EGFR, ERBB, ERBB1, HER1, PIG61, mENA |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 69.4 kD |
From 120.00€
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Human TNFSF11 Protein, hFc Tag
Item number: DIM-PME100100.10
Recombinant human TNFSF11 Protein with N-terminal Human Fc tag. hFc(Glu99-Ala330) TNFSF11(Ile140-Asp317), Protein function: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation....
| Keywords: | CD254, hRANKL2, ODF, OPGL, OPTB2, RANKL, sOdf, TNLG6B, TRANCE |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 48.4 kD |
From 124.00€
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Human CD46 Protein, His Tag
Item number: DIM-PME100102.10
Recombinant human CD46 Protein with C-terminal 6×His tag. CD46(Cys35-Tyr328) 6×His tag, Protein function: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of...
| Keywords: | CD46, AHUS2, MCP, MIC10, TLX, TRA2.10 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 33.5 kD |
From 105.00€
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Human TGFBR1 Protein, N-hFc Tag
Item number: DIM-PME100103.10
Recombinant human TGFBR1 Protein with N-terminal Human Fc tag. hFc(Glu99-Ala330) TGFBR1(Leu34-Leu126), Protein function: Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3....
| Keywords: | AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, tbetaR-I, TBR-i, TBRI, TGFR-1 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 36.3 kD |
From 105.00€
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Anti-VEGFA antibody(DMC276), IgG1 Chimeric mAb
Item number: DIM-DMC100276.10
Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin....
| Keywords: | Anti-MVCD1, Anti-VEGF, Anti-VPF, Anti-VEGFA antibody(DMC276), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-LGALS1 antibody(DMC277), IgG1 Chimeric mAb
Item number: DIM-DMC100277.10
Protein function: Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. [The...
| Keywords: | Anti-GAL1, Anti-GBP, Anti-LGALS1 antibody(DMC277), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-JAM-A antibody(DMC278), IgG1 Chimeric mAb
Item number: DIM-DMC100278.10
Protein function: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role...
| Keywords: | Anti-CD321, Anti-JAM, Anti-JAM1, Anti-JAMA, Anti-JCAM, Anti-KAT, Anti-PAM-1, Anti-JAM-A antibody(DMC278), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-Galectin 9 antibody(DMC279), IgG1 Chimeric mAb
Item number: DIM-DMC100279.10
Protein function: Binds galactosides (PubMed:18005988). Has high affinity for the Forssman pentasaccharide (PubMed:18005988). Ligand for HAVCR2/TIM3 (PubMed:16286920). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (PubMed:16286920). Also stimulates bactericidal activity in infected macrophages by...
| Keywords: | Anti-Galectin-9, Anti-LGALS9, Anti-Ecalectin, Anti-Gal-9, Anti-Galectin 9 antibody(DMC279), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-CD21 antibody(DMC280), IgG1 Chimeric mAb
Item number: DIM-DMC100280.10
Protein function: Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047). [The UniProt Consortium]
| Keywords: | Anti-C3DR, Anti-CD21, Anti-CR, Anti-CVID7, Anti-SLEB9, Anti-CD21 antibody(DMC280), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-AFP antibody(DMC281), IgG1 Chimeric mAb
Item number: DIM-DMC100281.10
Protein function: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. [The UniProt Consortium]
| Keywords: | Anti-AFPD, Anti-FETA, Anti-HPAFP, Anti-AFP antibody(DMC281), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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Anti-IL11RA antibody(DMC282), IgG1 Chimeric mAb
Item number: DIM-DMC100282.10
Protein function: Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal...
| Keywords: | Anti-IL-11 R alpha, Anti-IL-11 RA, Anti-IL11RA, Anti-Interleukin-11 receptor subunit alpha, Anti-IL-11 receptor subunit... |
| Host: | Rabbit |
| Species reactivity: | human |
From 145.00€
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