Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CEACAM5 (precemtabart biosimilar) mAb, biotinylated
Item number: DIM-BME100627B.100
Research use only. Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules,...
| Keywords: | M9140,M-9140,M 9140, Anti-CEA, Anti-CD66e, Anti-CEACAM5, Anti-Meconium antigen 100, Anti-Carcinoembryonic antigen,... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (pucotenlimab biosimilar) mAb
Item number: DIM-BME100629.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | HX-008,HX008,HX 008,HX-8,HX8,HX 8,Puyouheng, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 120.00€
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Anti-CTLA-4 (quavonlimab biosimilar) mAb
Item number: DIM-BME100632.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | AK-107,MK-1308,AK107,MK1308,AK 107,MK 1308, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4,... |
| Species reactivity: | human |
From 120.00€
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Anti-CD40 (ravagalimab biosimilar) mAb
Item number: DIM-BME100636.100
Research use only. Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | ABBV 323,ABBV-323,ABBV 323,PR 1629977,PR-1629977,PR1629977, Anti-Bp50, Anti-CD40, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L... |
| Species reactivity: | human |
From 120.00€
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Anti-C5 (ravulizumab biosimilar) mAb
Item number: DIM-BME100637.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | ALXN 1210,ALXN-1210,ALXN1210,ALXN 1810,ALXN-1810,ALXN1810,Ultomiris, Anti-C5, Anti-CPAMD4 |
| Species reactivity: | human |
From 120.00€
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Anti-PCSK9 (recaticimab biosimilar) mAb, biotinylated
Item number: DIM-BME100638B.100
Research use only. Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2...
| Keywords: | SHR-1209,SHR1209,SHR 1209, Anti-PC9, Anti-NARC1, Anti-PCSK9, Anti-NARC-1, Anti-PSEC0052, EC=3.4.21.-, Anti-Proprotein... |
| Species reactivity: | human |
From 145.00€
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Anti-VEGFB (reflocibart biosimilar) mAb, biotinylated
Item number: DIM-BME100640B.100
Research use only. Protein function: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. [The UniProt Consortium]
| Keywords: | CSL-346,CSL346,CSL 346,2H10, Anti-VRF, Anti-VEGFB, Anti-VEGF-B, Anti-VEGF-related factor, Anti-Vascular endothelial growth... |
| Species reactivity: | human |
From 145.00€
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Anti-APP (remternetug biosimilar) mAb, biotinylated
Item number: DIM-BME100641B.100
Research use only. Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis (PubMed:25122912). Involved in cell...
| Keywords: | LY-3372993,LY 3372993,LY3372993,N3pG 4,N3pG4,N3PG-IV, Anti-A4 |
| Species reactivity: | human |
From 145.00€
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Anti-TIGIT (renvistobart biosimilar) mAb
Item number: DIM-BME100643.100
Research use only. Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | BMS-986207,BMS 986207,BMS986207, Anti-TIGIT, Anti-VSIG9, Anti-T-cell immunoreceptor with Ig and ITIM domains, Anti-V-set... |
| Species reactivity: | human |
From 120.00€
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Anti-TIGIT (renvistobart biosimilar) mAb, biotinylated
Item number: DIM-BME100643B.100
Research use only. Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | BMS-986207,BMS 986207,BMS986207, Anti-TIGIT, Anti-VSIG9, Anti-T-cell immunoreceptor with Ig and ITIM domains, Anti-V-set... |
| Species reactivity: | human |
From 145.00€
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Anti-SOST (resugosbart biosimilar) mAb
Item number: DIM-BME100645.100
Research use only. Protein function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. [The UniProt Consortium]
| Keywords: | SHR-1222,SHR1222,SHR 1222, Anti-Sclerostin |
| Species reactivity: | human |
From 120.00€
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Anti-FOLR1 (rinatabart biosimilar) mAb, biotinylated
Item number: DIM-BME100651B.100
Research use only. Protein function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis...
| Keywords: | PRO-1184,PRO1184,PRO 1184, Anti-FBP, Anti-FOLR, Anti-FOLR1, Anti-FR-alpha, Anti-KB cells FBP, Anti-Folate receptor 1,... |
| Species reactivity: | human |
From 145.00€
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