Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CTLA-4 (muzastotug biosimilar) mAb, biotinylated
Item number: DIM-BME100577B.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | ADG126,ADG-126, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic... |
| Species reactivity: | human |
From 145.00€
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Anti-CCL24 (nebokitug biosimilar) mAb
Item number: DIM-BME100580.100
Research use only. Protein function: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. [The UniProt...
| Keywords: | TBC, Anti-CCL24, Anti-MPIF2, Anti-MPIF-2, Anti-CK-beta-6, Anti-Eotaxin-2, Anti-C-C motif chemokine 24,... |
| Species reactivity: | human |
From 120.00€
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Anti-EGFR (necitumumab biosimilar) mAb
Item number: DIM-BME100581.100
Research use only. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN,...
| Keywords: | IMC-11F8,IMC 11F8,IMC11F8,LY 3012211,LY3012211,LY-3012211,Portraza,Portrazza, Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene... |
| Species reactivity: | human |
From 120.00€
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Anti-LAG3 (negalstobart biosimilar) mAb
Item number: DIM-BME100582.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | IBI-110,IBI 110,IBI110, Anti-FDC |
| Species reactivity: | human |
From 120.00€
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Anti-LAG3 (negalstobart biosimilar) mAb, biotinylated
Item number: DIM-BME100582B.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | IBI-110,IBI 110,IBI110, Anti-FDC |
| Species reactivity: | human |
From 145.00€
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Anti-CD96 (nelistotug biosimilar) mAb, biotinylated
Item number: DIM-BME100584B.100
Research use only. Protein function: May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using...
| Keywords: | GSK 6097608,GSK-6097608,GSK6097608, Anti-CD96, Anti-Cell surface antigen CD96, Anti-T-cell surface protein tactile, Anti-T... |
| Species reactivity: | human |
From 145.00€
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Anti-EGFR (nimotuzumab biosimilar) mAb, biotinylated
Item number: DIM-BME100587B.100
Research use only. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN,...
| Keywords: | DE-766,DE766,DE 766,KI-0501,KI0501,KI 0501,KI-501,KI 501,KI501,KI-0502,KI0502,KI 0502,KI-502,KI502,KI... |
| Species reactivity: | human |
From 145.00€
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Anti-SORT1 (nivisnebart biosimilar) mAb
Item number: DIM-BME100589.100
Research use only. Protein function: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind...
| Keywords: | TBC, Anti-NT3, Anti-Gp95, Anti-NTR3, Anti-SORT1, Anti-Sortilin, Anti-Glycoprotein 95, Anti-100 kDa NT receptor,... |
| Species reactivity: | human |
From 120.00€
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Anti-SORT1 (nivisnebart biosimilar) mAb, biotinylated
Item number: DIM-BME100589B.100
Research use only. Protein function: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind...
| Keywords: | TBC, Anti-NT3, Anti-Gp95, Anti-NTR3, Anti-SORT1, Anti-Sortilin, Anti-Glycoprotein 95, Anti-100 kDa NT receptor,... |
| Species reactivity: | human |
From 145.00€
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Anti-CD19 (obexelimab biosimilar) mAb
Item number: DIM-BME100594.100
Research use only. Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling...
| Keywords: | AMG 729,AMG-729,AMG729,XmAb 5871,XmAb-5871, Anti-CD19, Anti-B-lymphocyte antigen CD19, Anti-Differentiation antigen CD19,... |
| Species reactivity: | human |
From 120.00€
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Anti-CD19 (obexelimab biosimilar) mAb, biotinylated
Item number: DIM-BME100594B.100
Research use only. Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling...
| Keywords: | AMG 729,AMG-729,AMG729,XmAb 5871,XmAb-5871, Anti-CD19, Anti-B-lymphocyte antigen CD19, Anti-Differentiation antigen CD19,... |
| Species reactivity: | human |
From 145.00€
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Anti-TIGIT (ociperlimab biosimilar) mAb, biotinylated
Item number: DIM-BME100596B.100
Research use only. Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | BGB-A1217,BGB A1217,WCD-118,WCD118,WCD 118, Anti-TIGIT, Anti-VSIG9, Anti-T-cell immunoreceptor with Ig and ITIM domains,... |
| Species reactivity: | human |
From 145.00€
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