Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-PD-L1 (lesabelimab biosimilar) mAb
Item number: DIM-BME100550.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | ADG104,ADG-104,LDP, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1,... |
| Species reactivity: | human |
From 120.00€
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Anti-CD47 (letaplimab biosimilar) mAb
Item number: DIM-BME100551.100
Research use only. Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of...
| Keywords: | IBI-188,IBI188,IBI 188, Anti-IAP, Anti-MER6, Anti-CD47, Anti-Protein MER6, Anti-Integrin-associated protein,... |
| Species reactivity: | human |
From 120.00€
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Anti-IL6R (levilimab biosimilar) mAb
Item number: DIM-BME100552.100
Research use only. Protein function: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal (PubMed:28265003). Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis...
| Keywords: | BCD 089,BCD-089,BCD089,BCD89,BCD-89,BCD 89,Ilsira, |
| Species reactivity: | human |
From 120.00€
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Anti-IGF-1R (lonigutamab biosimilar) mAb
Item number: DIM-BME100556.100
Research use only. Protein function: Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation...
| Keywords: | VB-421,VB421,VB 421, Anti-IGF1R, EC=2.7.10.1 |
| Species reactivity: | human |
From 120.00€
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Anti-IGF-1R (lonigutamab biosimilar) mAb, biotinylated
Item number: DIM-BME100556B.100
Research use only. Protein function: Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation...
| Keywords: | VB-421,VB421,VB 421, Anti-IGF1R, EC=2.7.10.1 |
| Species reactivity: | human |
From 145.00€
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Anti-SIRPalpha (lumistobart biosimilar) mAb, biotinylated
Item number: DIM-BME100558B.100
Research use only. Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May...
| Keywords: | BR105,BR-105,BR 105, Anti-Bit, Anti-p84, Anti-BIT, Anti-SIRPA, Anti-SHPS-1, Anti-CD172a, Anti-Sirp-alpha-1,... |
| Species reactivity: | human |
From 145.00€
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Anti-IL1A (lunlekitug biosimilar) mAb, biotinylated
Item number: DIM-BME100560B.100
Research use only. Protein function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and...
| Keywords: | XB20-12,XB2012,XB20 12, Anti-IL1A, Anti-IL1F1, Anti-IL-1 alpha, Anti-Hematopoietin-1, Anti-Interleukin-1 alpha |
| Species reactivity: | human |
From 145.00€
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Anti-Her2 (margetuximab biosimilar) mAb, biotinylated
Item number: DIM-BME100563B.100
Research use only. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for...
| Keywords: | MARGENZA,MGAH-22,MGAH 22,MGAH22, Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1,... |
| Species reactivity: | human |
From 145.00€
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Anti-Her2 (marstacimab biosimilar) mAb, biotinylated
Item number: DIM-BME100564B.100
Research use only. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for...
| Keywords: | PF-06741086,PF06741086,PF-6741086,PF6741086, Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1,... |
| Species reactivity: | human |
From 145.00€
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Anti-CD22 (mozistobart biosimilar) mAb
Item number: DIM-BME100575.100
Research use only. Protein function: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid. The sialic acid recognition site can be masked by cis interactions...
| Keywords: | TAC001,TAC-001,TAC 001, Anti-CD22, Anti-BL-CAM, Anti-SIGLEC2, Anti-Siglec-2, Anti-B-cell receptor CD22, Anti-T-cell... |
| Species reactivity: | human |
From 120.00€
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Anti-CD22 (mozistobart biosimilar) mAb, biotinylated
Item number: DIM-BME100575B.100
Research use only. Protein function: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid. The sialic acid recognition site can be masked by cis interactions...
| Keywords: | TAC001,TAC-001,TAC 001, Anti-CD22, Anti-BL-CAM, Anti-SIGLEC2, Anti-Siglec-2, Anti-B-cell receptor CD22, Anti-T-cell... |
| Species reactivity: | human |
From 145.00€
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Anti-CTLA-4 (muzastotug biosimilar) mAb
Item number: DIM-BME100577.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | ADG126,ADG-126, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic... |
| Species reactivity: | human |
From 120.00€
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