Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CD47 (ligufalimab biosimilar) mAb, biotinylated
Item number: DIM-BME100554B.100
Research use only. Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of...
| Keywords: | AK-117,AK117,AK 117, Anti-IAP, Anti-MER6, Anti-CD47, Anti-Protein MER6, Anti-Integrin-associated protein, Anti-Leukocyte... |
| Species reactivity: | human |
From 145.00€
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Anti-CD38 (lumrotatug biosimilar) mAb
Item number: DIM-BME100559.100
Research use only. Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. [The UniProt...
| Keywords: | CM313,CM-313, Anti-T10, Anti-CD38, Anti-ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, Anti-cADPr hydrolase 1, Anti-ADP-ribosyl... |
| Species reactivity: | human |
From 120.00€
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Anti-IL1A (lunlekitug biosimilar) mAb
Item number: DIM-BME100560.100
Research use only. Protein function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and...
| Keywords: | XB20-12,XB2012,XB20 12, Anti-IL1A, Anti-IL1F1, Anti-IL-1 alpha, Anti-Hematopoietin-1, Anti-Interleukin-1 alpha |
| Species reactivity: | human |
From 120.00€
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Anti-NGF (luvagrobart biosimilar) mAb
Item number: DIM-BME100561.100
Research use only. Protein function: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems (PubMed:14976160, PubMed:20978020). Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation,...
| Keywords: | AK115,AK-115, Anti-NGF, Anti-NGFB, Anti-Beta-NGF, Anti-Beta-nerve growth factor |
| Species reactivity: | human |
From 120.00€
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Anti-NGF (luvagrobart biosimilar) mAb, biotinylated
Item number: DIM-BME100561B.100
Research use only. Protein function: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems (PubMed:14976160, PubMed:20978020). Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation,...
| Keywords: | AK115,AK-115, Anti-NGF, Anti-NGFB, Anti-Beta-NGF, Anti-Beta-nerve growth factor |
| Species reactivity: | human |
From 145.00€
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Anti-IL4RA (manfidokimab biosimilar) mAb
Item number: DIM-BME100562.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | AK-120,AK120,AK 120, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 120.00€
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Anti-IL4RA (manfidokimab biosimilar) mAb, biotinylated
Item number: DIM-BME100562B.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | AK-120,AK120,AK 120, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 145.00€
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Anti-AXL (mipasetamab biosimilar) mAb
Item number: DIM-BME100569.100
Research use only. Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factor GAS6 and which is thus regulating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at...
| Keywords: | ADCT-601,ADCT601,ADCT 601,BGB 601,BGB-601,BGB601, Anti-UFO, Anti-AXL, EC=2.7.10.1, Anti-AXL oncogene,... |
| Species reactivity: | human |
From 120.00€
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Anti-Mesothelin (misitatug biosimilar) mAb, biotinylated
Item number: DIM-BME100572B.100
Research use only. Protein function: Membrane-anchored forms may play a role in cellular adhesion. [The UniProt Consortium]
| Keywords: | RC-88,RC88,RC 88, Anti-MPF, Anti-MSLN |
| Species reactivity: | human |
From 145.00€
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Anti-CD40 (mitazalimab biosimilar) mAb
Item number: DIM-BME100573.100
Research use only. Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | ADC 1013,ADC-1013,ADC1013,JNJ 7107,JNJ7107,JNJ-7107,JNJ-64457107,JNJ64457107,JNJ 64457107,Vanalimab, Anti-Bp50, Anti-CD40,... |
| Species reactivity: | human |
From 120.00€
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Anti-TIGIT (ralzapastotug biosimilar) mAb
Item number: DIM-BME100635.100
Research use only. Protein function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. [The UniProt Consortium]
| Keywords: | AB-308,AB308,AB 308, Anti-TIGIT, Anti-VSIG9, Anti-T-cell immunoreceptor with Ig and ITIM domains, Anti-V-set and... |
| Species reactivity: | human |
From 120.00€
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Anti-CD40 (ravagalimab biosimilar) mAb, biotinylated
Item number: DIM-BME100636B.100
Research use only. Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | ABBV 323,ABBV-323,ABBV 323,PR 1629977,PR-1629977,PR1629977, Anti-Bp50, Anti-CD40, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L... |
| Species reactivity: | human |
From 145.00€
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