Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CD40 (cifurtilimab biosimilar) mAb
Item number: DIM-BME100454.100
Research use only. Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | hS2C6nf, Anti-Bp50, Anti-CD40, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L receptor, Anti-B-cell surface antigen CD40, Anti-Tumor... |
| Species reactivity: | human |
From 120.00€
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Anti-CD40 (cifurtilimab biosimilar) mAb, biotinylated
Item number: DIM-BME100454B.100
Research use only. Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | hS2C6nf, Anti-Bp50, Anti-CD40, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L receptor, Anti-B-cell surface antigen CD40, Anti-Tumor... |
| Species reactivity: | human |
From 145.00€
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Anti-CLDN18 (ciletatug biosimilar) mAb, biotinylated
Item number: DIM-BME100455B.100
Research use only. Protein function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [The UniProt Consortium]
| Keywords: | TBC, Anti-CLDN18, Anti-Claudin-18 |
| Species reactivity: | human |
From 145.00€
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Anti-TFPI (concizumab biosimilar) mAb, biotinylated
Item number: DIM-BME100458B.100
Research use only. Protein function: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. [The UniProt...
| Keywords: | mAb-2021,mAb2021,NN-7415,NN7415, Anti-EPI, Anti-LACI, Anti-TFPI, Anti-Extrinsic pathway inhibitor, Anti-Tissue factor... |
| Species reactivity: | human |
From 145.00€
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Anti-Her2 (coprelotamab biosimilar) mAb, biotinylated
Item number: DIM-BME100459B.100
Research use only. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for...
| Keywords: | GB 221,GB221,GB-221, Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu,... |
| Species reactivity: | human |
From 145.00€
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Anti-TTR (coramitug biosimilar) mAb
Item number: DIM-BME100460.100
Research use only. Protein function: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. [The UniProt Consortium]
| Keywords: | NNC6019,NNC-6019,PRX004,PRX-004, Anti-TTR, Anti-TBPA, Anti-PALB, Anti-ATTR, Anti-Prealbumin, Anti-Transthyretin |
| Species reactivity: | human |
From 120.00€
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Anti-PD-L1 (cosibelimab biosimilar) mAb
Item number: DIM-BME100461.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | CK 301,CK301,CK-301,TG 1501,TG1501,TG-1501, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1, Anti-B7 homolog 1,... |
| Species reactivity: | human |
From 120.00€
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Anti-C5 (crovalimab biosimilar) mAb
Item number: DIM-BME100463.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | CH 7092230,CH7092230,CH-7092230,RG 6107,RG-6107,RG6107,RO 7092230,RO-7112689,RO7112689,SKY 59,SKY-59,SKY59, Anti-C5,... |
| Species reactivity: | human |
From 120.00€
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Anti-C5 (crovalimab biosimilar) mAb, biotinylated
Item number: DIM-BME100463B.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | CH 7092230,CH7092230,CH-7092230,RG 6107,RG-6107,RG6107,RO 7092230,RO-7112689,RO7112689,SKY 59,SKY-59,SKY59, Anti-C5,... |
| Species reactivity: | human |
From 145.00€
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Anti-Trop2 (datopotamab biosimilar) mAb, biotinylated
Item number: DIM-BME100469B.100
Research use only. Protein function: May function as a growth factor receptor. [The UniProt Consortium]
| Keywords: | DS 1062a,DS1062a,DS-1062a,DS-1062,DS1062,S-1062a,S1062a, Anti-GA733-1, Anti-TACSTD2, Anti-Cell surface glycoprotein... |
| Species reactivity: | human |
From 145.00€
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Anti-IFNB1 (dazukibart biosimilar) mAb, biotinylated
Item number: DIM-BME100470B.100
Research use only. Protein function: Has antiviral, antibacterial and anticancer activities. [The UniProt Consortium]
| Keywords: | PF-06823859,PF06823859, Anti-IFB, Anti-IFNB1, Anti-IFN-beta, Anti-Interferon beta, Anti-Fibroblast interferon |
| Species reactivity: | human |
From 145.00€
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Anti-TFRC (delpacibart biosimilar) mAb
Item number: DIM-BME100471.100
Research use only. Protein function: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738). Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a...
| Keywords: | AOC1001,AOC-1001, Anti-TFRC |
| Species reactivity: | human |
From 120.00€
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