Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-TLR4 (paridiprubart biosimilar) mAb
Item number: DIM-BME100611.100
Research use only. Protein function: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:27022195). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:9237759, PubMed:10835634,...
| Keywords: | EB 05,EB05,EB-05,EB 5,EB-5,EB5,EB-07,EB07,EB-07,EB-7,EB7,EB 7,NI-0101,NI 0101,NI0101,NI-101,NI101,NI 101, Anti-TLR4,... |
| Species reactivity: | human |
From 120.00€
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Anti-TLR4 (paridiprubart biosimilar) mAb, biotinylated
Item number: DIM-BME100611B.100
Research use only. Protein function: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:27022195). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:9237759, PubMed:10835634,...
| Keywords: | EB 05,EB05,EB-05,EB 5,EB-5,EB5,EB-07,EB07,EB-07,EB-7,EB7,EB 7,NI-0101,NI 0101,NI0101,NI-101,NI101,NI 101, Anti-TLR4,... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (penpulimab biosimilar) mAb
Item number: DIM-BME100613.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | AK 105,AK105,AK 105, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 120.00€
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Anti-PD-1 (peresolimab biosimilar) mAb
Item number: DIM-BME100615.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | LY-3462817,LY3462817,LY 3462817, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 120.00€
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Anti-LILRB2 (polzastobart biosimilar) mAb
Item number: DIM-BME100622.100
Research use only. Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042). Involved in the down-regulation of the immune response and the development of...
| Keywords: | JTX-8064,JTX8064,JTX 8064, Anti-ILT-4, Anti-LIR-2, Anti-CD85d, Anti-MIR-10, Anti-Immunoglobulin-like transcript 4,... |
| Species reactivity: | human |
From 120.00€
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Anti-SNCA (prasinezumab biosimilar) mAb, biotinylated
Item number: DIM-BME100626B.100
Research use only. Protein function: Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic...
| Keywords: | NEOD-002,NEOD002,NEOD 002,NEOD-2,NEOD2,NEOD 2,PRX-002,PRX002,PRX 002,PRX-2,PRX2,PRX 2,RG 7935,RG7935,RG-7935,RO... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (prolgolimab biosimilar) mAb
Item number: DIM-BME100628.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | BCD-100, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 120.00€
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Anti-VEGFR2 (pulocimab biosimilar) mAb
Item number: DIM-BME100630.100
Research use only. Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and...
| Keywords: | AK-109, AK109,AK 109, Anti-KDR, Anti-FLK1, Anti-FLK-1, Anti-CD309, Anti-VEGFR-2, Anti-Fetal liver kinase 1, Anti-Kinase... |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H4 (puxitatug biosimilar) mAb
Item number: DIM-BME100631.100
Research use only. Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in...
| Keywords: | AZD-8205, AZD 8205, AZD8205, Anti-B7-H4, Anti-B7h.5, Anti-B7 homolog 4, Anti-Protein B7S1, Anti-T-cell costimulatory... |
| Species reactivity: | human |
From 120.00€
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Anti-IL4RA (rademikibart biosimilar) mAb
Item number: DIM-BME100634.100
Research use only. Protein function: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic...
| Keywords: | CBP 201,CBP-201, CBP201, Anti-IL4R, Anti-IL4RA, Anti-582J2.1 |
| Species reactivity: | human |
From 120.00€
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Anti-CD117 (barzolvolimab biosimilar) mAb, biotinylated
Item number: DIM-BME100423B.100
Research use only. Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in...
| Keywords: | CDX-0159,CDX0159, Anti-PBT, Anti-KIT, Anti-SCFR, Anti-CD117, Anti-p145 c-kit, EC=2.7.10.1, Anti-Proto-oncogene c-Kit,... |
| Species reactivity: | human |
From 145.00€
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Anti-TNFRSF10B (benufutamab biosimilar) mAb
Item number: DIM-BME100430.100
Research use only. Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of...
| Keywords: | GEN1029,GEN-1029,Hx-DR5-01,Hx-DR5-05,iDD 004,iDD-004,iDD004, Anti-DR5, Anti-CD262, Anti-TRAIL-R2, Anti-TNFRSF10B,... |
| Species reactivity: | human |
From 120.00€
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