Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-C5 (greziprubart biosimilar) mAb
Item number: DIM-BME100527.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | TBC, Anti-C5, Anti-CPAMD4 |
| Species reactivity: | human |
From 120.00€
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Anti-C5 (greziprubart biosimilar) mAb, biotinylated
Item number: DIM-BME100527B.100
Research use only. Protein function: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. [The UniProt...
| Keywords: | TBC, Anti-C5, Anti-CPAMD4 |
| Species reactivity: | human |
From 145.00€
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Anti-LAG3 (ieramilimab biosimilar) mAb, biotinylated
Item number: DIM-BME100531B.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | IMP-701,IMP 701,IMP701,LAG-525,LAG525,LAG 525,NVP-LAG525, Anti-FDC |
| Species reactivity: | human |
From 145.00€
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Anti-FCGRT (imeroprubart biosimilar) mAb
Item number: DIM-BME100534.100
Research use only. Protein function: Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk (PubMed:7964511, PubMed:10933786). IgG in the milk is bound at the apical surface of...
| Keywords: | TBC, Anti-FcRn, Anti-FCRN, Anti-FCGRT, Anti-Neonatal Fc receptor, Anti-IgG receptor FcRn large subunit p51, Anti-IgG Fc... |
| Species reactivity: | human |
From 120.00€
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Anti-CCR8 (imzokitug biosimilar) mAb
Item number: DIM-BME100536.100
Research use only. Protein function: Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. [The UniProt Consortium]
| Keywords: | BMS 986340,BMS-986340,BMS986340, Anti-TER1, Anti-CCR8, Anti-CCR-8, Anti-CKRL1, Anti-CDw198, Anti-GPRCY6, Anti-CKR-L1,... |
| Species reactivity: | human |
From 120.00€
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Anti-IL17A (ixekizumab biosimilar) mAb
Item number: DIM-BME100543.100
Research use only. Protein function: Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:24120361). Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with...
| Keywords: | LY-2439821,LY2439821,LY 2439821,Taltz, Anti-IL-17, Anti-CTLA8, Anti-IL17A, Anti-CTLA-8, Anti-IL-17A, Anti-Interleukin-17A,... |
| Species reactivity: | human |
From 120.00€
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Anti-IL17A (ixekizumab biosimilar) mAb, biotinylated
Item number: DIM-BME100543B.100
Research use only. Protein function: Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:24120361). Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with...
| Keywords: | LY-2439821,LY2439821,LY 2439821,Taltz, Anti-IL-17, Anti-CTLA8, Anti-IL17A, Anti-CTLA-8, Anti-IL-17A, Anti-Interleukin-17A,... |
| Species reactivity: | human |
From 145.00€
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Anti-SORT1 (latozinemab biosimilar) mAb
Item number: DIM-BME100547.100
Research use only. Protein function: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind...
| Keywords: | AL-001,AL001,AL 001,AL1,AL-1,AL 1,GSK-4527223,GSK4527223,GSK 4527223, Anti-NT3, Anti-Gp95, Anti-NTR3, Anti-SORT1,... |
| Species reactivity: | human |
From 120.00€
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Anti-IL13 (lebrikizumab biosimilar) mAb
Item number: DIM-BME100548.100
Research use only. Protein function: Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324)....
| Keywords: | DRM 06,DRM-06,DRM06,DRM 6,DRM-6,DRM6,LY 3650150,LY-3650150,LY3650150,MILR1444A,MILR-1444A,MILR 1444,ARG... |
| Species reactivity: | human |
From 120.00€
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Anti-APP (lecanemab biosimilar) mAb, biotinylated
Item number: DIM-BME100549B.100
Research use only. Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis (PubMed:25122912). Involved in cell...
| Keywords: | BAN-2401,BAN2401,BAN 2401,Leqembi, Anti-A4 |
| Species reactivity: | human |
From 145.00€
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Anti-PD-L1 (lesabelimab biosimilar) mAb, biotinylated
Item number: DIM-BME100550B.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | ADG104,ADG-104,LDP, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1,... |
| Species reactivity: | human |
From 145.00€
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Anti-IL6R (levilimab biosimilar) mAb, biotinylated
Item number: DIM-BME100552B.100
Research use only. Protein function: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal (PubMed:28265003). Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis...
| Keywords: | BCD 089,BCD-089,BCD089,BCD89,BCD-89,BCD 89,Ilsira, |
| Species reactivity: | human |
From 145.00€
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