Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-PCSK9 (evolocumab biosimilar) mAb
Item number: DIM-BME100501.100
Research use only. Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2...
| Keywords: | AMG-145,AMG145,Repatha, Anti-PC9, Anti-NARC1, Anti-PCSK9, Anti-NARC-1, Anti-PSEC0052, EC=3.4.21.-, Anti-Proprotein... |
| Species reactivity: | human |
From 120.00€
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Anti-4-1BB (evunzekibart biosimilar) mAb
Item number: DIM-BME100502.100
Research use only. Protein function: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. [The UniProt Consortium]
| Keywords: | ATOR-1017,ATOR1017, Anti-CD137, Anti-CDw137, Anti-TNFRSF9, Anti-T-cell antigen ILA, Anti-4-1BB ligand receptor,... |
| Species reactivity: | human |
From 120.00€
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Anti-PD-1 (ezabenlimab biosimilar) mAb, biotinylated
Item number: DIM-BME100505B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | BI-754091,BI754091, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 145.00€
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Anti-LAG3 (favezelimab biosimilar) mAb, biotinylated
Item number: DIM-BME100507B.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | MK-4280,MK4280, Anti-FDC |
| Species reactivity: | human |
From 145.00€
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Anti-LAG3 (fianlimab biosimilar) mAb, biotinylated
Item number: DIM-BME100512B.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | REGN-3767,REGN3767, Anti-FDC |
| Species reactivity: | human |
From 145.00€
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Anti-CTLA-4 (firastotug biosimilar) mAb
Item number: DIM-BME100514.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | ADG-116,ADG116,ADG 116, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic... |
| Species reactivity: | human |
From 120.00€
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Anti-CD40 Ligand (frexalimab biosimilar) mAb
Item number: DIM-BME100516.100
Research use only. Protein function: Cytokine that acts as a ligand to CD40/TNFRSF5 (PubMed:1280226, PubMed:31331973). Costimulates T-cell proliferation and cytokine production (PubMed:8617933). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction...
| Keywords: | INX 021,INX021,INX-021,SAR-441344,SAR441344,SAR 441344, Anti-CD40L, Anti-CD40LG |
| Species reactivity: | human |
From 120.00€
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Anti-EGFR (futuximab biosimilar) mAb, biotinylated
Item number: DIM-BME100518B.100
Research use only. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN,...
| Keywords: | DS-992,DS992,S-95026,S95206,Sym-004 (Combination with Modotuximab),Sym004 (Combination with Modotuximab), Anti-ERBB,... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-L1 (garivulimab biosimilar) mAb, biotinylated
Item number: DIM-BME100520B.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | BGB-A333,BGB A333, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1,... |
| Species reactivity: | human |
From 145.00€
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Anti-IL1B (gevokizumab biosimilar) mAb, biotinylated
Item number: DIM-BME100522B.100
Research use only. Protein function: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and...
| Keywords: | S-78989,S78989,S 78989,VPM 087,VPM087,VPM-087,VPM87,VPM-87,XMA-005.2,XMA-0052,XMA52,XOMA-052,XOMA052,XOMA52,XOMA-52,... |
| Species reactivity: | human |
From 145.00€
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Anti-CD40 (giloralimab biosimilar) mAb
Item number: DIM-BME100523.100
Research use only. Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | ABBV-927,ABBV927, Anti-Bp50, Anti-CD40, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L receptor, Anti-B-cell surface antigen CD40,... |
| Species reactivity: | human |
From 120.00€
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Anti-LOX-1 (golocdacimab biosimilar) mAb
Item number: DIM-BME100525.100
Research use only. Protein function: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in...
| Keywords: | MEDI-6570,MEDI 6570,MEDI6570, Anti-OLR1, Anti-CLEC8A |
| Species reactivity: | human |
From 120.00€
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