Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CD40 (abiprubart biosimilar) mAb
Item number: DIM-BME100401.100
Research use only. Protein function: Receptor for TNFSF5/CD40LG (PubMed:31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [The UniProt Consortium]
| Keywords: | KPL404,KPL-404,KPL 404, Anti-Bp50, Anti-CD40, Anti-CDw40, Anti-TNFRSF5, Anti-CD40L receptor, Anti-B-cell surface antigen... |
| Species reactivity: | human |
From 120.00€
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Anti-PD-1 (acrixolimab biosimilar) mAb
Item number: DIM-BME100402.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | YBL-006, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 120.00€
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Anti-PD-1 (acrixolimab biosimilar) mAb, biotinylated
Item number: DIM-BME100402B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | YBL-006, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 145.00€
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Anti-CXCL8 (adakitug biosimilar) mAb, biotinylated
Item number: DIM-BME100403B.100
Research use only. Protein function: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on...
| Keywords: | BMS-986253,BMS986253,HuMax-IL8,HuMax-Inflam,MDX018,MDX-018, Anti-IL8, Anti-CXCL8 |
| Species reactivity: | human |
From 145.00€
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Anti-PD-L1 (adebrelimab biosimilar) mAb
Item number: DIM-BME100404.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | HTI-1088,HTI1088,HTI-1316,HTI1316,SHR 1316,SHR1316,SHR-1316, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1,... |
| Species reactivity: | human |
From 120.00€
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Anti-PD-L1 (adebrelimab biosimilar) mAb, biotinylated
Item number: DIM-BME100404B.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | HTI-1088,HTI1088,HTI-1316,HTI1316,SHR 1316,SHR1316,SHR-1316, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1,... |
| Species reactivity: | human |
From 145.00€
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Anti-LAG3 (alcestobart biosimilar) mAb
Item number: DIM-BME100406.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | TBC, Anti-FDC |
| Species reactivity: | human |
From 120.00€
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Anti-LAG3 (alcestobart biosimilar) mAb, biotinylated
Item number: DIM-BME100406B.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | TBC, Anti-FDC |
| Species reactivity: | human |
From 145.00€
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Anti-SIGLEC15 (aldastotug biosimilar) mAb
Item number: DIM-BME100407.100
Research use only. Protein function: Binds sialylated glycoproteins. [The UniProt Consortium]
| Keywords: | BSI 060T,BSI-060T,BSI060T,PYX 106,PYX-106,PYX106, Anti-CD33L3, Anti-SIGLEC15, Anti-Siglec-15, Anti-CD33 antigen-like 3,... |
| Species reactivity: | human |
From 120.00€
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Anti-IL18 (aletekitug biosimilar) mAb
Item number: DIM-BME100408.100
Research use only. Protein function: A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory...
| Keywords: | TBC, Anti-IGIF, Anti-IL-18, Anti-IL-1 gamma, Anti-Iboctadekin, Anti-Interleukin-18, Anti-Interleukin-1 gamma,... |
| Species reactivity: | human |
From 120.00€
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Anti-PCSK9 (alirocumab biosimilar) mAb
Item number: DIM-BME100409.100
Research use only. Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2...
| Keywords: | Praluent,REGN-727,REGN727,SAR-236553, Anti-PC9, Anti-NARC1, Anti-PCSK9, Anti-NARC-1, Anti-PSEC0052, EC=3.4.21.-,... |
| Species reactivity: | human |
From 120.00€
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Anti-PCSK9 (alirocumab biosimilar) mAb, biotinylated
Item number: DIM-BME100409B.100
Research use only. Protein function: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2...
| Keywords: | Praluent,REGN-727,REGN727,SAR-236553, Anti-PC9, Anti-NARC1, Anti-PCSK9, Anti-NARC-1, Anti-PSEC0052, EC=3.4.21.-,... |
| Species reactivity: | human |
From 145.00€
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