Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-TSLP (ecleralimab biosimilar) mAb, biotinylated
Item number: DIM-BME100485B.100
Research use only. Protein function: [Isoform 1]: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. [The UniProt Consortium]
| Keywords: | CSJ-117,CSJ117,NOV-14,NOV14, Anti-TSLP, Anti-Thymic stromal lymphopoietin |
| Species reactivity: | human |
From 145.00€
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Anti-CD117 (eglatoprutug biosimilar) mAb, biotinylated
Item number: DIM-BME100487B.100
Research use only. Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in...
| Keywords: | TBC, Anti-PBT, Anti-KIT, Anti-SCFR, Anti-CD117, Anti-p145 c-kit, EC=2.7.10.1, Anti-Proto-oncogene c-Kit, Anti-Piebald... |
| Species reactivity: | human |
From 145.00€
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Anti-CD39 (eltivutabart biosimilar) mAb
Item number: DIM-BME100488.100
Research use only. Protein function: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. [The UniProt Consortium]
| Keywords: | TBC, Anti-CD39, Anti-ENTPD1, Anti-NTPDase 1, EC=3.6.1.5, Anti-Ecto-apyrase, Anti-Ecto-ATPase 1, Anti-Ecto-ATPDase 1,... |
| Species reactivity: | human |
From 120.00€
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Anti-CSF1R (emactuzumab biosimilar) mAb
Item number: DIM-BME100489.100
Research use only. Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes....
| Keywords: | RG-7155,RG7155,RO-5509554,RO5509554, Anti-FMS, Anti-CD115, Anti-CSF1R, Anti-CSF-1R, Anti-CSF-1-R, Anti-M-CSF-R,... |
| Species reactivity: | human |
From 120.00€
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Anti-B7-H4 (emiltatug biosimilar) mAb, biotinylated
Item number: DIM-BME100490B.100
Research use only. Protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T- cells (Treg), in...
| Keywords: | XMT-1660,XMT1660,XMT 1660, Anti-B7-H4, Anti-B7h.5, Anti-B7 homolog 4, Anti-Protein B7S1, Anti-T-cell costimulatory... |
| Species reactivity: | human |
From 145.00€
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Anti-C2 (empasiprubart biosimilar) mAb
Item number: DIM-BME100491.100
Research use only. Protein function: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. [The UniProt Consortium]
| Keywords: | ARGX-117,ARGX117, Anti-C2, EC=3.4.21.43 |
| Species reactivity: | human |
From 120.00€
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Anti-TNFRSF1B (emunkitug biosimilar) mAb
Item number: DIM-BME100493.100
Research use only. Protein function: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects...
| Keywords: | TBC, Anti-TNFBR, Anti-TNFRSF1B |
| Species reactivity: | human |
From 120.00€
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Anti-LAG3 (encelimab biosimilar) mAb
Item number: DIM-BME100494.100
Research use only. Protein function: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells (PubMed:7805750, PubMed:8647185, PubMed:20421648). Delivers inhibitory signals upon binding to ligands, such as FGL1. FGL1 constitutes a major ligand of LAG3 and is responsible for LAG3 T-cell...
| Keywords: | GSK-4074386,GSK4074386,TSR 033,TSR033,TSR-033, Anti-FDC |
| Species reactivity: | human |
From 120.00€
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Anti-PD-1 (enlonstobart biosimilar) mAb, biotinylated
Item number: DIM-BME100495B.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | SG 001,SG-001,SG001, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 145.00€
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Anti-SIRPalpha (epacmarstobart biosimilar) mAb, biotinylated
Item number: DIM-BME100496B.100
Research use only. Protein function: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May...
| Keywords: | GS0189,GS-0189,GS189,GS-189,FSI189,FSI-189, Anti-Bit, Anti-p84, Anti-BIT, Anti-SIRPA, Anti-SHPS-1, Anti-CD172a,... |
| Species reactivity: | human |
From 145.00€
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Anti-CD38 (erzotabart biosimilar) mAb
Item number: DIM-BME100497.100
Research use only. Protein function: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. [The UniProt...
| Keywords: | GEN-3014,GEN3014,GEN 3014, Anti-T10, Anti-CD38, Anti-ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, Anti-cADPr hydrolase 1,... |
| Species reactivity: | human |
From 120.00€
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Anti-CTLA-4 (evalstotug biosimilar) mAb
Item number: DIM-BME100500.100
Research use only. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
| Keywords: | BA3071,BA-3071, Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic... |
| Species reactivity: | human |
From 120.00€
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