Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Anti-CXCL8 (adakitug biosimilar) mAb
Item number: DIM-BME100403.100
Research use only. Protein function: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on...
| Keywords: | BMS-986253,BMS986253,HuMax-IL8,HuMax-Inflam,MDX018,MDX-018, Anti-IL8, Anti-CXCL8 |
| Species reactivity: | human |
From 120.00€
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Anti-IL18 (aletekitug biosimilar) mAb, biotinylated
Item number: DIM-BME100408B.100
Research use only. Protein function: A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory...
| Keywords: | TBC, Anti-IGIF, Anti-IL-18, Anti-IL-1 gamma, Anti-Iboctadekin, Anti-Interleukin-18, Anti-Interleukin-1 gamma,... |
| Species reactivity: | human |
From 145.00€
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Anti-CD73 (ansipastobart biosimilar) mAb, biotinylated
Item number: DIM-BME100413B.100
Research use only. Protein function: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. [The UniProt Consortium]
| Keywords: | BR101,BR-101,BR 101, Anti-NT5, Anti-CD73, Anti-NT5E, Anti-5'-NT, EC=3.1.3.5, Anti-5'-nucleotidase, Anti-Ecto-5'-nucleotidase |
| Species reactivity: | human |
From 145.00€
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Anti-TFPI (armocibart biosimilar) mAb, biotinylated
Item number: DIM-BME100416B.100
Research use only. Protein function: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. [The UniProt...
| Keywords: | TBC, Anti-EPI, Anti-LACI, Anti-TFPI, Anti-Extrinsic pathway inhibitor, Anti-Tissue factor pathway inhibitor,... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-1 (balstilimab biosimilar) mAb
Item number: DIM-BME100422.100
Research use only. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2 (PubMed:21276005). Following T-cell...
| Keywords: | AGEN-2034,AGEN2034,RebmAb-700,RebmAb700, Anti-CD279, Anti-hPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Species reactivity: | human |
From 120.00€
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Anti-EGFR (becotatug biosimilar) mAb
Item number: DIM-BME100425.100
Research use only. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN,...
| Keywords: | JMT101,JMT-101, Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Species reactivity: | human |
From 120.00€
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Anti-TFPI (befovacimab biosimilar) mAb
Item number: DIM-BME100426.100
Research use only. Protein function: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. [The UniProt...
| Keywords: | BAY-109,BAY109,BAY-1093884,BAY1093884, Anti-EPI, Anti-LACI, Anti-TFPI, Anti-Extrinsic pathway inhibitor, Anti-Tissue... |
| Species reactivity: | human |
From 120.00€
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Anti-IL7RA (bempikibart biosimilar) mAb
Item number: DIM-BME100428.100
Research use only. Protein function: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). [The UniProt Consortium]
| Keywords: | ADX-914,ADX914, Anti-IL7R, Anti-CD127, Anti-IL-7RA, Anti-CDw127, Anti-IL-7R-alpha, Anti-IL-7R subunit alpha, Anti-IL-7... |
| Species reactivity: | human |
From 120.00€
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Anti-TNFRSF10B (benufutamab biosimilar) mAb, biotinylated
Item number: DIM-BME100430B.100
Research use only. Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of...
| Keywords: | GEN1029,GEN-1029,Hx-DR5-01,Hx-DR5-05,iDD 004,iDD-004,iDD004, Anti-DR5, Anti-CD262, Anti-TRAIL-R2, Anti-TNFRSF10B,... |
| Species reactivity: | human |
From 145.00€
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Anti-MAPT (bepranemab biosimilar) mAb, biotinylated
Item number: DIM-BME100431B.100
Research use only. Protein function: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein...
| Keywords: | RG-6416,RG6416,UCB-0107,UCB0107, Anti-MAPTL, Anti-PHF-tau, Anti-Paired helical filament-tau, Anti-Neurofibrillary tangle... |
| Species reactivity: | human |
From 145.00€
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Anti-PD-L1 (betifisolimab biosimilar) mAb, biotinylated
Item number: DIM-BME100433B.100
Research use only. Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response...
| Keywords: | MSB-2311,MSB2311, Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1,... |
| Species reactivity: | human |
From 145.00€
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Anti-TSLP (bosakitug biosimilar) mAb, biotinylated
Item number: DIM-BME100438B.100
Research use only. Protein function: [Isoform 1]: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. [The UniProt Consortium]
| Keywords: | BSI-045B,BSI-04502,BSI045B,BSI04502,TQC2731,TQC-2731, Anti-TSLP, Anti-Thymic stromal lymphopoietin |
| Species reactivity: | human |
From 145.00€
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