Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human 5HT3B-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120780.10
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in...
| Keywords: | HTR3B, 5-HT3B, 5-HT3-B, Serotonin receptor 3B, 5-hydroxytryptamine receptor 3B |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 50.3 kD |
From 1,185.00€
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Human 5HT3C-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120781.10
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in...
| Keywords: | HTR3C, 5-HT3C, 5-HT3-C, Serotonin receptor 3C, 5-hydroxytryptamine receptor 3C |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 50.2 kD |
From 1,185.00€
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Human 5HT3E-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120783.10
This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been...
| Keywords: | HTR3E, 5-HT3E, 5-HT3-E, Serotonin receptor 3E, 5-hydroxytryptamine receptor 3E |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 51.4 kD |
From 1,185.00€
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Human ACHA4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120787.10
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an...
| Keywords: | CHRNA4, NACRA4, Neuronal acetylcholine receptor subunit alpha-4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 70 kD |
From 1,185.00€
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Human ACHA5-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120788.10
The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been...
| Keywords: | CHRNA5, NACHRA5, Neuronal acetylcholine receptor subunit alpha-5 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 53.1 kD |
From 1,185.00€
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Human ACHA7-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120790.10
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular...
| Keywords: | CHRNA7, NACHRA7, Neuronal acetylcholine receptor subunit alpha-7 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 56.4 kD |
From 1,185.00€
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Human ACHA9-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120791.10
This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair...
| Keywords: | CHRNA9, NACHRA9, NACHR alpha-9, Neuronal acetylcholine receptor subunit alpha-9, Nicotinic acetylcholine receptor subunit... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 54.8 kD |
From 1,185.00€
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Human ACH10-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120792.10
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including...
| Keywords: | CHRNA10, NACHRA10, NACHR alpha-10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 49.7 kD |
From 1,185.00€
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Human ACHB2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120794.10
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This...
| Keywords: | CHRNB2, Neuronal acetylcholine receptor subunit beta-2 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 57 kD |
From 1,185.00€
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Human ACHB4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120796.10
This gene is found within a conserved gene cluster and encodes one of the beta subunits of the nicotinic acetylcholine receptor (nAChRs) superfamily which form ligand-gated ion channels with a central pore that forms a cation channel. Neuronal nAChRs are pentameric structures that can be either homomeric or...
| Keywords: | CHRNB4, Neuronal acetylcholine receptor subunit beta-4 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 56.4 kD |
From 1,185.00€
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Human ACHG-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120799.10
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third...
| Keywords: | CHRNG, ACHRG, Acetylcholine receptor subunit gamma |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 57.9 kD |
From 1,185.00€
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Human GBRA3-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120802.10
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A...
| Keywords: | GABRA3, GABA(A) receptor subunit alpha-3, Gamma-aminobutyric acid receptor subunit alpha-3 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 55.2 kD |
From 1,185.00€
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