Products from DIMA Biotech
DIMA Biotechnology specializes in preclinical research and development solutions for the Biopharma industry. The extensive portfolio includes more than 1,200 antibodies and over 1,500 proteins and cytokines. The proteins also include a wide range of full-length transmembrane proteins, for which DIMA has developed several platforms, including nanodiscs, virus-like particles, membrane nanoparticles and exosomes. All platforms are based on mammalian expression systems and produce full-length membrane proteins as soluble protein products with native conformation and activity.
More information at: www.dimabio.com
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Human TRPC5-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120758.10
This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone...
| Keywords: | TRP5, TRP-5, hTRP5, TRPC5, TrpC5, hTRP-5, Transient receptor protein 5, Short transient receptor potential channel 5 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 111.4 kD |
From 1,185.00€
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Human TRPC7-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120760.10
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular...
| Keywords: | TRP7, hTRP7, TrpC7, TRPC7, TRP-7, Transient receptor protein 7, Short transient receptor potential channel 7 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 99.6 kD |
From 1,185.00€
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Human TRPM1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120761.10
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause...
| Keywords: | LTrpC1, Melastatin-1, Long transient receptor potential channel 1, Transient receptor potential cation channel subfamily M... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 182.2 kD |
From 1,185.00€
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Human TRPM2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120762.10
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript...
| Keywords: | TrpC7, TRPM2, LTrpC2, LTrpC-2, Transient receptor potential channel 7, Transient receptor potential melastatin 2, Long... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 171.2 kD |
From 1,185.00€
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Human TRPM4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120764.10
The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport...
| Keywords: | LTRPC4, hTRPM4, LTrpC4, LTrpC-4, Melastatin-4, Long transient receptor potential channel 4, Calcium-activated... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 134.3 kD |
From 1,185.00€
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Human TRPM5-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120765.10
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that...
| Keywords: | LTrpC5, LTrpC-5, MLSN1- and TRP-related gene 1 protein, Long transient receptor potential channel 5, Transient receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 131.5 kD |
From 1,185.00€
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Human TRPM6-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120766.10
This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney....
| Keywords: | CHAK2, TRPM6, EC=2.7.11.1, Channel kinase 2, Melastatin-related TRP cation channel 6, Transient receptor potential cation... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 231.7 kD |
From 1,185.00€
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Human MCLN1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120769.10
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2 ),...
| Keywords: | ML4, ML1, MG-2, TRPML1, MSTP080, Mucolipin-1, Mucolipidin, Transient receptor potential channel mucolipin 1 |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 65 kD |
From 1,185.00€
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Human PK2L1-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120773.10
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation...
| Keywords: | PKD2L1, Polycystin-L, Polycystin-L1, Polycystin-2L1, Polycystin-2 homolog, Polycystic kidney disease 2-like 1 protein |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 92 kD |
From 1,185.00€
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Human TRPV2-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120775.10
This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. [provided by RefSeq, Jul...
| Keywords: | VRL, TRPV2, TrpV2, VRL-1, OTRPC2, Osm-9-like TRP channel 2, Vanilloid receptor-like protein 1, Transient receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 86 kD |
From 1,185.00€
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Human TRPV4-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120777.10
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2 -permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure....
| Keywords: | VRL2, TRPV4, VRL-2, TrpV4, TRP12, VR-OAC, OTRPC4, Osm-9-like TRP channel 4, Vanilloid receptor-like protein 2, Vanilloid... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 98.3 kD |
From 1,185.00€
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Human TRPV5-Strep full length protein-synthetic nanodisc
Item number: DIM-FLP120778.10
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and...
| Keywords: | ECaC, CaT2, TrpV5, TRPV5, ECaC1, OTRPC3, Osm-9-like TRP channel 3, Calcium transport protein 2, Epithelial calcium channel... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 82.6 kD |
From 1,185.00€
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